Search for dissertations about: "Mohammad Hamdy Abdelrazak Morsy"

Found 1 swedish dissertation containing the words Mohammad Hamdy Abdelrazak Morsy.

2. 1. Genome-wide epigenetic profiling of B cell leukemia and lymphoma

   Author : Mohammad Hamdy Abdelrazak Morsy; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CLL; PRC2; EZH2; Epigenetics; CpG islands; DNA methylation; ChIP-seq; RNA-seq;

   Abstract : Epigenetic modifications, at the level of DNA methylation and post-translational modifications of histone tails cooperatively function in the organization of the genome, and thereby establish the gene expression profiles, phenotypes, and cellular fates. In this work, we investigated the aberrant epigenome in chronic lymphocytic leukemia (CLL) which is one of the most frequent lymphoid malignancies in the west including the Nordic countries. READ MORE