Search for dissertations about: "Molecular Dissociation"
Showing result 6 - 10 of 204 swedish dissertations containing the words Molecular Dissociation.
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6. Development of molecular recognition by rational and combinatorial engineering
Abstract : Combinatorial protein engineering, taking advantage of large libraries of protein variants and powerful selection technology, is a useful strategy for developing affinity proteins for applications in biotechnology and medicine. In this thesis, two small affinity proteins have been subjected to combinatorial protein engineering to improve or redirect the binding. READ MORE
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7. Determinants of peptidyl-tRNA drop-off from E. coli Ribosomes : Effects of antibiotics, mutations and translation factors
Abstract : During protein synthesis, some peptidyl-tRNA molecules dissociate from the ribosomes and become hydrolysed by peptidyl-tRNA hydrolase (Pth). Two different in vitro systems, poly(U) and natural mRNA programmed ribosomes, have been used in order to determine dissociation (drop-off) rates of deacylated- and peptidyl-tRNAs from different sites on ribosomes. READ MORE
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8. Molecular Interplay of Antibiotics on the Bacterial Ribosome
Abstract : Inhibition of protein synthesis is one of the most common modes of action for medically useful antibiotics. This thesis presents the mechanistic studies of two chemically distinct classes of antibiotics that target bacterial ribosomes –aminoglycosides and thermorubin. READ MORE
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9. Single-cell RNA sequencing as a tool to study panarthropod evolution
Abstract : Panarthropoda is a monophyletic group comprised of arthropods and lobopods, molting animals with a segmented body, paired appendages, dorsal brain, and ventral nerve cords. Evolutionary Developmental Biology (EvoDevo) is an interdisciplinary field that seeks to understand how changes in development form the basis for variations in morphology and phenotypic evolution, including the genetic network underlying these processes. READ MORE
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10. Ultrafast Photoionization Dynamics Studied with Coincidence Momentum Imaging Spectrometers
Abstract : The time scale of the dynamics in atoms and molecules varies from attoseconds (10-18) to picoseconds (10-12) depending on the size of the particles. To study such dynamics, ultrafast light pulses are needed to trigger and capture the reaction. One of the most direct methods consists in ionizing the system and observing the following response. READ MORE