Search for dissertations about: "Molecular Docking Screens"
Found 3 swedish dissertations containing the words Molecular Docking Screens.
-
1. Molecular simulations of G protein-coupled receptors : A journey into structure-based ligand design and receptor function
Abstract : The superfamily of G protein-coupled receptors (GPCRs) contains a large number of important drug targets. These cell surface receptors recognize extracellular signaling molecules, which stimulates intracellular pathways that play major roles in human physiology. READ MORE
-
2. Membrane Stress and the Role of GYF Domain Proteins
Abstract : Intracellular membrane trafficking is regulated by a large number of protein complexes and lipids. Blocking of trafficking disrupts normal membrane dynamics and causes membrane stress. READ MORE
-
3. The impact of GPCR structures on understanding receptor function and ligand binding
Abstract : G protein-coupled receptors (GPCRs) form the largest superfamily of eukaryotic membrane proteins and are responsible for the action of nearly 30% of all marketed drugs. For a long period, efforts to study these receptors were limited by the paucity of atomic-resolution structural information. READ MORE