Search for dissertations about: "Molecular Medicine"
Showing result 1 - 5 of 2783 swedish dissertations containing the words Molecular Medicine.
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1. Two Types of Fibrils in ATTR Amyloidosis Implications for Clinical Phenotype and Treatment Outcome
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Systemic amyloidoses are a group of lethal diseases where proteins aggregate into fibrillar structures, called amyloid fibrils, that deposits throughout the body. Transthyretin (TTR) causes one type of amyloidosis, in which the aggregates mainly infiltrate nervous and cardiac tissue. READ MORE
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2. Assessment of Novel Molecular Prognostic Markers in Chronic Lymphocytic Leukemia
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : The clinical course of chronic lymphocytic leukemia (CLL) is highly heterogeneous, which has prompted the search for biomarkers that can predict prognosis in this disease. The IGHV gene mutation status and certain genomic aberrations have been identified as reliable prognostic markers of clinical outcome for this disorder. READ MORE
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3. Insulin Resistance Causes, biomarkers and consequences
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : The worldwide increasing number of persons affected by largely preventable diseases like diabetes demands better prevention and treatment. Insulin is required for effective utilisation of circulating nutrients. READ MORE
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4. Genetic and Epigenetic Profiling of Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL) both belong to the group of mature B-cell malignancies. However, MCL is typically clinically aggressive while the clinical course of CLL varies. READ MORE
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5. In Vitro Drug Sensitivity and Apoptosis in Chronic Lymphocytic Leukemia
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Chronic lymphocytic leukemia (CLL) is a heterogeneous malignancy displaying varying clinical outcome, where molecular markers today can divide patients into prognostic subgroups. Despite the introduction of new agents for treatment, remissions are usually not sustained in CLL and resistance towards treatment can partly be explained by aberrant apoptosis. READ MORE
