Search for dissertations about: "Molecular Subtypes"

Showing result 1 - 5 of 191 swedish dissertations containing the words Molecular Subtypes.

  2. 1. Molecular Characterization of Bladder Cancer Subtypes

    Author : Pontus Eriksson; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bladder Cancer; Urothelial Carcinoma; Molecular Subtypes; Genomic Characterization; Gene Expression;

    Abstract : Bladder cancer is one of the most common malignancies world-wide, and in Sweden approximately 3000 cases are diagnosed annually. Even though bladder cancer is so common there is low public awareness of the disease, and it has historically been less studied compared to other common types of cancer. READ MORE

  4. 2. Metabolic Risk Factors and Molecular Subtypes of Colorectal Cancer

    Author : Robin Myte; Bethany van Guelpen; Richard Palmqvist; Jenny Häggström; Matty Weijenberg; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Colorectal cancer; risk factors; metabolic syndrome; one-carbon metabolism; molecular subtypes; KRAS; BRAF; MSI; molecular pathological epidemiology; Cancer Epidemiology; cancerepidemiologi;

    Abstract : Background: Colorectal cancer (CRC) is a heterogeneous disease developing from distinct pathways, resulting in tumor subtypes with large differences in clinical and molecular characteristics. Molecular characteristics are increasingly being used clinically to guide therapy. READ MORE

  5. 3. Streptococcal immunoglobulin degrading enzymes of the IdeS and IgdE family

    Author : Christian Spoerry; Ulrich von Pawel-Rammingen; Heiko Herwald; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Streptococcus; S. pyogenes; S. agalactiae; S. suis; S. porcinus; S. pseudoporcinus; S. equi subsp. zooepidemicus; protease; immunoglobulin; immune evasion; IdeS; IgdE; molekylärbiologi; Molecular Biology;

    Abstract : Bacteria of the genus Streptococcus are common asymptomatic colonisers of humans and animals. As opportunistic pathogens they can however, depending on their host’s immune status and other circumstances, cause mild to very severe infections. READ MORE

  6. 4. Satellite cells in human skeletal muscle : molecular identification quantification and function

    Author : Mona Lindström; Lars-Eric Thornell; Hannu Kalimo; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; satellite cell markers; NCAM; Pax7; MyoD; myogenin; DLK1 FA1; c-Met; human skeletal muscle; immunohistochemistry; muscle growth; muscle hypertrophy; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; anatomi; Human Anatomy;

    Abstract : Skeletal muscle satellite cells located between the plasma membrane and the basal lamina of muscle fibres, could for many years, only be studied in situ by electron microscopy. The introduction of immunohistochemistry and the discovery of molecular markers of satellite cells then made them accessible for light microscopic studies and a wealth of information is today available. READ MORE

  7. 5. Aspects of interferon alpha signalling in hematopoetic cells

    Author : Lennart Carlsson; erik lundgren; Ulrich Kalinke; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; interferon; human; B-lymphocyte; survival; proliferation; myeloma; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The type I interferons (IFN) are a family of cytokines with pleiothropic activities that include inhibition of viral replication, cell proliferation and activation of the immune system. These properties give the IFNs important physiological and pathological roles in infection and cancer and have led to their therapeutic use for many clinical conditions. READ MORE