Search for dissertations about: "Molecular genetics"
Showing result 16 - 20 of 509 swedish dissertations containing the words Molecular genetics.
-
16. Genetic studies on Systemic Lupus Erythematosus : A fine mapping and candidate gene approach
Abstract : Linkage in the 2q37 region was evaluated using microsatellite markers in multi-case families from Sweden, Iceland and Norway. Both the two-point and the multipoint linkage analysis show highly significant LOD scores (Z=4.51 and 6.03, respectively). READ MORE
-
17. Effects of Selection and Demography on DNA Polymorphism in Black Mustard (Brassica nigra)
Abstract : The evolution of three genes from the CONSTANS-LIKE gene family is studied in Brassica nigra. We use a combination of population genetic and phylogenetic techniques in order to assess the relative importance of selection and demography on the pattern of DNA variation. READ MORE
-
18. A Genetic Survey of the Pathogenic Parasite Trypanosoma cruzi
Abstract : Trypanosoma cruzi, the causative agent of Chagas´ disease, is an evolutionarily ancient species with distinct biological and immunological characteristics. A fundamental understanding of the basic biology of the parasite is necessary in order to develop reliable therapeutic and prophylactic agents against T. cruzi. We have, as a part of the T. READ MORE
-
19. Genetic and Epigenetic Profiling of Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia
Abstract : Mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL) both belong to the group of mature B-cell malignancies. However, MCL is typically clinically aggressive while the clinical course of CLL varies. READ MORE
-
20. The Effects of Mutation and Selection on the Rate and Pattern of Molecular Evolution in Birds
Abstract : By comparing sequence diversity and divergence on sex chromosomes one can study how the rate of evolution in affected by mutation and/or selection. The rate of mutation in male biased, meaning that relatively more mutations are created in the male germ line than in the female. READ MORE