Search for dissertations about: "Molekylär biofysik"

Showing result 6 - 10 of 74 swedish dissertations containing the words Molekylär biofysik.

  2. 6. Flash Diffractive Imaging in Three Dimensions

    Author : Tomas Ekeberg; Janos Hajdu; Keith Nugent; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; X-ray; diffraction; mimivirus; three dimensional; phase retrieval; EMC; manifold embedding; CXI; FEL; free-electron laser; single particle; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : During the last years we have seen the birth of free-electron lasers, a new type of light source ten billion times brighter than syncrotrons and able to produce pulses only a few femtoseconds long. One of the main motivations for building these multi-million dollar machines was the prospect of imaging biological samples such as proteins and viruses in 3D without the need for crystallization or staining. READ MORE

  4. 7. Small Particles with Big Impact : Structural Studies of Viruses and Toxicological Studies of Nanodiamonds

    Author : Anna Munke; Marvin Seibert; Kenta Okamoto; Filipe Maia; Inger Andersson; Nicola Stonehouse; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Chaetenuissarnavirus II; cryo-EM; CtenRNAV-II; Escherichia coli; Danio rerio; flash X-ray imaging; Marnaviridae; single-particle analysis; single-particle imaging; Sogarnavirus; virus evolution; virus structure; XFEL; zebrafish embryo; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

    Abstract : Nanoparticles (NPs) can be found everywhere and their existence has both beneficial and harmful consequences for the environment and living beings. The investigations on which this thesis is based upon have contributed to an increased understanding of some of these particles and to the development of a method that could be used to study their structure. READ MORE

  5. 8. Structural Studies of Large dsDNA Viruses using Single Particle Methods

    Author : Hemanth Kumar Narayana Reddy; Martin Svenda; Sarah Butcher; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PR772; phage; PRD1; Bacteriophage; coliphage; Melbournevirus; Cedratvirus; lurbo; Pithovirus; CryoEM; Single particle imaging; Coherent; Diffractive; Imaging; Soft X-ray; Microscopy; Microscope; GDVN; High resolution; XFEL; aerosol; Injection; electrospray; gas dynamic virtual nozzle; CDI; CXI; FEL; Chemistry with specialization in Biophysics; Kemi med inriktning mot biofysik;

    Abstract : Structural studies of large biological assemblies pose a unique problem due to their size, complexity and heterogeneity. Conventional methods like x-ray crystallography, NMR, etc. are limited in their ability to address these issues. To overcome some of these limitations, single particle methods were used. READ MORE

  6. 9. Imaging Living Cells with an X-ray Laser

    Author : Gijs van der Schot; Tomas Ekeberg; Janos Hajdu; Filipe Maia; Pierre Thibault; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Coherent diffractive X-ray imaging; flash X-ray imaging; lensless imaging; single particle imaging; cyanobacteria; phasing; image classification; substrate-free sample delivery; X-ray free-electron laser; XFEL; FEL; CDXI; CDI; CXI; FXI; Chemistry with specialization in Biophysics; Kemi med inriktning mot biofysik;

    Abstract : Imaging living cells at a resolution higher than the resolution of optical microscopy is a significant challenge. Fluorescence microscopy can achieve a degree of super-resolution via labeling cellular components with a fluorescent dye. READ MORE

  7. 10. Coherent Diffractive Imaging with X-ray Lasers

    Author : Max Felix Hantke; Filipe R. N. C. Maia; Janos Hajdu; Martin Svenda; Edgar Weckert; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; coherent diffractive X-ray imaging; lensless imaging; coherent X-ray diffractive imaging; flash diffractive imaging; single particle imaging; aerosol injection; electrospray injection; substrate-free sample delivery; carboxysome; phase retrieval; X-ray diffraction software; X-ray free-electron laser; XFEL; FEL; CXI; CDI; CXDI; FXI;

    Abstract : The newly emerging technology of X-ray free-electron lasers (XFELs) has the potential to revolutionise molecular imaging. XFELs generate very intense X-ray pulses and predictions suggest that they may be used for structure determination to atomic resolution even for single molecules. READ MORE