Search for dissertations about: "Molekylär cellbiologi"

Showing result 1 - 5 of 110 swedish dissertations containing the words Molekylär cellbiologi.

  1. 1. Control of lateral root development in Arabidopsis thaliana

    University dissertation from Umeå : Sveriges Lantbruksuniversitet

    Author : Jan Eklöf; [2001]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Physiological Botany; fysiologisk botanik; molecular cell biology; molekylär cellbiologi;

    Abstract : .... READ MORE

  2. 2. Cross-regulation between TGFβ/BMP Signalling and the metabolic LKB1 pathway

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erna Raja; Aristidis Moustakas; Tomi Mäkelä; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cell signalling; TGFbeta; BMP; LKB1; AMPK; Molekylär cellbiologi; Molecular Cellbiology;

    Abstract : Cell signalling determines physiological responses to many cellular stimuli and environmental changes. The transforming growth factor-beta (TGFβ)/bone morphogenetic protein (BMP) signalling pathways begin by binding of ligand to the heterodimeric receptor complex, followed by activation of Smads that translocate to the nucleus to regulate transcription of genes that further mediate cellular physiology. READ MORE

  3. 3. Anaplastic Lymphoma Kinase mutations and downstream signalling

    University dissertation from Umeå : Umeå Universitet

    Author : Christina Schönherr; Ruth H Palmer; Aristidis Moustakas; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Anaplastic Lymphoma Kinase; oncogene; RTK; neuroblastoma; crizotinib; NVP-TAE684; gain-of-function; MYCN; transcription factor; small GTPase; Rap1; C3G; PC12 cells; neurite outgrowth; molecular cell biology; molekylär cellbiologi;

    Abstract : The oncogene Anaplastic Lymphoma Kinase (ALK) is a Receptor Tyrosine Kinase (RTK) and was initially discovered as the fusion protein NPM (nucleophosmin)-ALK in a subset of Anaplastic Large Cell Lymphomas (ALCL). Since then more fusion proteins have been identified in a variety of cancers. READ MORE

  4. 4. Regulation of cellular Hsp70 Proteostasis and aggregate management

    University dissertation from Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Author : Jayasankar Mohanakrishnan Kaimal; Claes Andréasson; Pierre Goloubinoff; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Proteins have to be folded to their native structures to be functionally expressed. Misfolded proteins are proteotoxic and negatively impact on cellular fitness. To maintain the proteome functional proteins are under the constant surveillance of dedicated molecular chaperones that perform protein quality control (PQC). READ MORE

  5. 5. Controlling protein homeostasis through regulation of Heat shock factor 1

    University dissertation from Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Author : Anna E. Masser; Claes Andréasson; Marie Öhman; David Pincus; [2019]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; stress; protein homeostasis; molecular chaperones; heat shock response; Hsf1; Hsp70; Saccharomyces cerevisiae; molekylär biovetenskap; Molecular Bioscience;

    Abstract : In order to thrive in a changing environment all organisms need to ensure protein homeostasis (proteostasis). Proteostasis is ensured by the proteostasis system that monitors the folding status of the proteome and regulates cell physiology and gene expression to counteract any perturbations. READ MORE