Search for dissertations about: "Molekylärmedicin"

Showing result 21 - 25 of 74 swedish dissertations containing the word Molekylärmedicin.

  2. 21. Tissue Factor and CD40 Ligand : Markers for the Interplay of Coagulation and Inflammation in the Acute Coronary Syndrome

    Author : Anders Mälarstig; Agneta Siegbahn; Lars Wallentin; Taavo Tenno; Fiona Green; Uppsala universitet; []
    Keywords : Molecular medicine; tissue factor; CD40 ligand; gene expression; single nucleotide polymorphism; acute coronary syndrome; myocardial infarction; coagulation; inflammation; Molekylärmedicin;

    Abstract : BACKGROUND: Tissue factor (TF) is a 47 kDa transmembrane glycoprotein known as the main initiator of blood coagulation. CD40 ligand is another membrane molecule, which ligates to cell types associated with atherosclerotic plaques thereby mediating intraplaque inflammation and weakening of the fibrous cap. READ MORE

  4. 22. Antibody Mediated Radionuclide Targeting of HER-2 for Cancer Diagnostics and Therapy : Preclinical Studies

    Author : Mikael Persson; Per-Uno Malmström; Vladimir Tolmachev; Jörgen Carlsson; Marion De Jong; Uppsala universitet; []
    Keywords : Molecular medicine; Neoplasm Antibodies; Targeted Radiotherapy; Radionuclide Imaging; Molekylärmedicin;

    Abstract : Targeted radionuclide therapy (TRT) holds great promise for the treatment of cancer. In TRT, radioactive nuclides are delivered specifically to tumours by molecules that recognise and bind to structures overexpressed by, or specific to, cancer cells. READ MORE

  5. 23. Angiogenic growth factors : mechanism of action and function in vascular development

    Author : Charlotte Rolny; Andrius Kazlauskas; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; PDGF-BB; VEGF; angiogenesis; hypoxia; migration; heparin; Molekylärmedicin; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Molecular Medicine; molekylär medicin genetik och patologi ;

    Abstract : The mature vascular system is composed of a network of blood vessels organized into arteries, capillaries, and veins. The vessels are composed of endothelial cells surrounded by smooth muscle cells and embedded in a specialized basement membrane. READ MORE

  6. 24. Functional Genomics of Bone Metabolism : Novel Candidate Genes Identified by Studies in Chicken Models

    Author : Carl-Johan Rubin; Andreas Kindmark; Östen Ljunggren; Leif Andersson; David Burt; Uppsala universitet; []
    Keywords : Molecular medicine; QTL; Bone; Osteoporosis; Gene expression; Microarray; Domestication; Molekylärmedicin;

    Abstract : Osteoporosis is a disease that leads to decreased bone mineral density (BMD), an altered bone micro-architecture and fragile bones. The disease is highly heritable and numerous genes are thought to be involved, making it difficult to identify the causative genetic elements. READ MORE

  7. 25. Development and Application of Triple Specific Proximity Ligation Assays (3PLA)

    Author : Edith Schallmeiner; Ulf Landegren; Larry Gold; Uppsala universitet; []
    Keywords : Molecular medicine; proxmity ligation; method development; cell siganling; Molekylärmedicin;

    Abstract : After the completion of the human genome project the human genome was annotated with the surprisingly small amount of 24 000 (www.ensemble.com) genes. READ MORE