Search for dissertations about: "Monoclonal immunology"

Showing result 1 - 5 of 54 swedish dissertations containing the words Monoclonal immunology.

  1. 1. Monoclonal antibodies to human interferon-α and interferon-γ : Characterization and application with focus on interferon-γ as a T cell cytokine

    University dissertation from Stockholm : Stockholm University

    Author : Gudrun Andersson; Stockholms universitet.; [1992]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; immunologi; Immunology;

    Abstract : The major functions of the immune system are to combat infections and to control that normal auto-immunity does not turn into auto-aggression. Antibodies, together with T cell receptors and MHC molecules, dictates the immunological specificity. READ MORE

  2. 2. B cell activation in vitro: thymus-dependent immune responses and bacterial cell surface proteins

    University dissertation from Center for Molecular Biomedicine, Lund University

    Author : Karol Axcrona; Lund University.; Lunds universitet.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nuclear transport; bacterial Ig-binding proteins; CD40L promoter; CD21; Ig; B lymphocyte activation in vitro; CD40; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : In this thesis aspects of peripheral B lymphocyte differentiation were studied. Through in vitro experiments, B lymphocyte activation was assessed. B lymphocytes express immunoglobulin (Ig) specific for a certain antigen on the cell surface, and when surface Ig is crosslinked by an antigen, the cell is activated. READ MORE

  3. 3. Immunological characteristics of a C-terminal fragment of the Plasmodium falciparum blood-stage antigen Pf332

    University dissertation from Stockholm : Wenner-Grens institut för experimentell biologi

    Author : Halima Aramide Balogun; Stockholms universitet.; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES Biology Cell and molecular biology Immunology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi; immunologi; Immunology;

    Abstract : Till date, there are no effective control strategies against the deadly disease of malaria, and millions of children across Africa, Oceania, Asia, and Latin America are at the mercy of this long term enemy of man every second that passes by. Other control measures combined with vaccination might help improve control strategy against malaria, but the development of vaccines face various challenges as well, due to the complexity of the parasites’ life cycle and other host factors. READ MORE

  4. 4. Analysis of effector pathways in arthritis

    University dissertation from Medical Inflammation Research, Department of Experimental Medicine, Faculty of Medicine, Lund University

    Author : Nandakumar Kutty Selva; Lund University.; Lunds universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; transplantation; Genetik; cytogenetics; Arthritis; mice; monoclonal antibody; collagen type II; Histology; histochemistry; cytochemistry; Histologi; tissue culture; cytokemi; histokemi; Genetics; vävnadskultur; serologi; cytogenetik; Immunology; serology;

    Abstract : Rheumatoid arthritis (RA) is a multifactorial, polygenic autoimmune disease. For effective treatment and control of RA, understanding of disease pathways and identification of genes involved are essential. Animal models are efficient tools to identify such pathogenic mechanisms and genes underlying the disease process. READ MORE

  5. 5. B cell deviations and type 1 diabetes in the NOD mouse

    University dissertation from Umeå : Umeå Universitet

    Author : Mia Sundström; Umeå universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Type 1 diabetes; Autoimmunity; NOD mouse; Idd; TACI; Immune response; Immune complex; immunologi; Immunology;

    Abstract : Type 1 diabetes (T1D) is a chronic autoimmune disease in which the insulin producing β-cells in the pancreatic islets of Langerhans are selectively attacked by the immune system. The β-cells are destroyed resulting in a reduced or eliminated insulin production, which in turn lead to a high blood glucose level. READ MORE