Search for dissertations about: "Monocytes Macrophages"
Showing result 1 - 5 of 144 swedish dissertations containing the words Monocytes Macrophages.
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1. Monocytes and macrophages, with a focus of Crohn's disease
Abstract : Monocytes and macrophages are part of the body’s first line of defense, eliminating pathogens by phagocytosis or by releasing a broad array of inflammatory mediators, such as cytokines, chemokines and proteases. In humans, three subsets of monocytes are described with seemingly different functions. READ MORE
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2. Cancer and Inflammation : Role of Macrophages and Monocytes
Abstract : Macrophages are cells of the innate immune system that can be found in large quantities in cancer tumors and affect cancer progression by regulating growth and invasiveness of cancer cells. There are two main phenotypes of macrophages denoted M1 and M2. READ MORE
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3. TNFalpha expression in monocytes/macrophages
Abstract : The recognition of microbes or microbial products by leukocytes is a key event in innate immunity. Binding of microbial products to cell surface receptors on phagocytes induce a response that includes the production of inflammatory mediators. One such mediator is the cytokine tumour necrosis factor alpha (TNF). READ MORE
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4. Eosinophil Cationic Protein : Expression Levels and Polymorphisms
Abstract : The eosinophil cationic protein (ECP) is usually associated with the eosinophil granulocyte. In this thesis the presence and production of this protein has been studied in two other cells. The circulating monocyte was found to contain ECP mRNA and small amounts of ECP, one thousand times less than that found in the eosinophil. READ MORE
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5. It Takes Two to Tango : Bacterial heterogeneity and host cell features govern Salmonella infection
Abstract : Salmonella enterica serovar Typhimurium (S.Tm) causes enterocolitis with significant worldwide morbidity and mortality. The general aim of this thesis is to investigate variation in host cell invasion mechanisms used by S.Tm across different host cell contexts, as well as the influence of bacterial cell-cell heterogeneity on invasion-relevant S. READ MORE