Advanced search

Showing result 16 - 20 of 376 swedish dissertations matching the above criteria.

  2. 16. Macrophage-material surface interactions

    Author : Christina Gretzer; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apoptosis; biomaterials; cell-cell interactions; cell-material interactions; cytokines; differentiation; fibrinogen; hydrogen peroxide; LPS; monocytes; particles;

    Abstract : Material surface-stimulated activation of the macrophage and the release of mediators has been suggested to be an important factor for inflammation and tissue regeneration around biomedical implants. Macrophage interactions with particles released from implants as well as macophage-bacteria interactions are also involved in implant loosening processes. READ MORE

  4. 17. The osteogenic potential of human mesenchymal stem cells: Novel markers and key factors for differentiation

    Author : Cecilia Granéli; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stem cells; Mesenchymal stromal cells; Osteogenic differentiation; Adipogenic differentiation; Bone regeneration; Inflammation; Monocytes; Infection; Bacterial membrane vesicles; Compromised bone healing; Cell surface proteins; CD-markers; Osseointegration; Regenerative medicine;

    Abstract : Mesenchymal stem cells are multipotent stem cells with ability to differentiate into cells of the connective tissue lineage, such as adipocytes, osteoblasts and chondrocytes, both in vitro and in vivo. The main objective of the present thesis was to study different aspects of the osteogenic potential of MSCs. READ MORE

  5. 18. Biomarkers in sepsis and other severe infections

    Author : Helena Janols; Enheten för infektionssjukdomar; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunosuppression; myeloid-derived suppressor cells; T cells; dendritic cells; monocytes; sepsis; Biomarkers;

    Abstract : Infectious diseases constitute a major global health problem. The presenting clinical picture results from a mixture of direct toxic actions by the microbiological agent and of the immune response mounted by the host. READ MORE

  6. 19. Immunological effects of isolated regional perfusion in malignant melanoma

    Author : Junko Johansson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanoma; Isolated regional perfusion; ILP; IHP; Melphalan; Immunogenic cell death; T cells; Monocytes; ISG;

    Abstract : Malignant melanoma patients with metastatic disease confined to the limbs or liver may be treated with hyperthermic isolated regional perfusion with a chemotherapeutic agent, most commonly melphalan. This procedure enables much higher tissue concentrations of the chemotherapeutic agent compared with systemic administration. READ MORE

  7. 20. Immune maturation in early childhood and the influence of herpesvirus infections

    Author : Ebba Sohlberg; Eva Sverremark-Ekström; Eleanor Riley; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Immune differentiation; monocytes; NK cells; B cells; T cells; Epstein-Barr virus; EBV; cytomegalovirus; CMV; IFN-γ; immunologi; Immunology;

    Abstract : The quality of immune responses develops from birth into adulthood and in the context of the host microbial environment. The aim of this work was to study immune maturation during childhood, and how this process can be affected by the common herpesviruses; Epstein-Barr virus (EBV) and cytomegalovirus (CMV). READ MORE