Search for dissertations about: "Multicentre study"

Showing result 6 - 10 of 122 swedish dissertations containing the words Multicentre study.

  2. 6. Study of Resistance in Hepatitis C Virus Prior to Treatment with Direct Acting Antivirals

    Author : Midori Kjellin; Johan Lennerstrand; Nina Weis; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C; HCV; DAA; RAS; resistance-associated substitution; baseline resistance; NS5A; NS3; SVR; Medical Virology; Medicinsk virologi; Mikrobiologi; Microbiology; Infektionssjukdomar; Infectious Diseases;

    Abstract : The rapid advancement of Hepatitis C (HCV) treatment presents a great challenge to clinicians in optimising therapy for their patients. Genotype (GT), efficacy, side-effects, drug combinations and treatment durations must be tailored to individual patients, considering comorbidities, degree of fibrosis, adherence and antiviral resistance. READ MORE

  4. 7. Daily Experiences and Perceived Quality of Care for Patients with Liver Cirrhosis

    Author : Maria Hjorth; Fredrik Rorsman; Elenor Kaminsky; Anncarin Svanberg; Daniel Sjöberg; Anna Forsberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liver cirrhosis; Multi-centre study; Nursing care; Patient experiences; Pragmatic clinical trial; Qualitative research; Quality of care; Caring Sciences; Vårdvetenskap;

    Abstract : Aim and methods: This thesis aimed to study patients’ experiences with illness in their day-to-day lives and their perceived quality of care before and after implementing a 24-month adjunctive registered nurse-based outpatient intervention in liver cirrhosis. Qualitative data was used to explore patient perspectives on day-to-day life and healthcare experiences related to liver cirrhosis. READ MORE

  5. 8. The Swedish Infant High-grade Reflux Trial - and a Focus group study of parents’ experiences

    Author : Josefin Nordenström; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; infant; high-grade vesicoureteral reflux; randomised; endoscopic treatment; antibiotic prophylaxis; renal damage; urinary tract infection; bladder function; parents experiences; focus group;

    Abstract : Background: Vesicoureteral reflux (VUR) is a pathological back-flow of urine from the bladder to the ureter and renal pelvis. VUR is associated with an increased risk of urinary tract infections (UTI) and renal damages. READ MORE

  6. 9. Rectal cancer surgery : Defunctioning stoma, anastomotic leakage and postoperative monitoring

    Author : Peter Matthiessen; Olof Hallböök; Rune Sjödahl; Lars Påhlman; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anterior resection of the rectum; total mesorectal excision; TME; anastomotic leakage; defunctioning stoma; risk factors; intraoperative adverse events; population based study; postoperative monitoring; CT-scan microdialysis; cytokines; Surgery; Kirurgi;

    Abstract : The understanding of the mesorectal spread in rectal cancer has lead to wide acceptance of total mesorectal excision (TME) as the surgical technique of choice for carcinoma in the lower and mid rectum. While oncological results and survival have improved with TME-surgery, morbidity and mortality remain important issues. READ MORE

  7. 10. Studies on anti-dsDNA Antibodies and other potential biomarkers in Systemic Lupus Erythematosus

    Author : Michele Compagno; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic Lupus Erythematosus Anti-dsDNA antibodies Biomarkers Osteopontin S100A8 A9 LE-cells Diagnostic accuracy Longitudinal study Multicentre study;

    Abstract : Systemic Lupus Erythematosus (SLE) is characterized by chronic inflammation involving many organ systems. The etiology is unknown and the pathogenesis has not been fully elucidated. Impairments of the immune system and of the mechanisms regulating cell death are commonly seen in SLE patients. READ MORE