Search for dissertations about: "Multifocal tumors"
Showing result 1 - 5 of 9 swedish dissertations containing the words Multifocal tumors.
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1. Computational studies of mutational sequence signatures in cancer genomes
Abstract : Cancer typically forms when mutational processes modify key cancer driver genes, resulting in positive selection and tumor growth. As such, mutational processes are at the core of the disease. Trinucleotide mutational signatures have emerged in the last decade as essential tools for analysis of mutational processes. READ MORE
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2. Studies on human polyomavirus infection in immunosuppressed patients with polyoma related tumors
Abstract : Polyomaviruses are potentially oncogenic viruses, found in humans, in other mammals and in birds all over the world. The polyomaviruses that have been observed in humans are BK virus (BKV) and JC virus (JCV) as well as the primate polyomavirus Simian Virus 40 (SV40). READ MORE
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3. Identification and characterization of candidate genes for neuroblastoma development
Abstract : Neuroblastoma (NB) is the most common tumor during infancy. It arises from undifferentiated cells in the sympathetic nervous system and is characterized by both clinical and genetic heterogeneity. One of the features of NBs with unfavorable outcome is loss on distal chromosome 1p. READ MORE
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4. Breast cancer : Multifocality, heterogeneity, and related genetic signatures
Abstract : Breast carcinoma often exhibits a complex subgross morphology and may occupy a large volume of the breast tissue and show unifocal, multifocal or diffuse growth patterns. Expression of estrogen- and progesterone receptors, HER2 overexpression, tumor grade, and proliferative activity allows us to classify breast carcinoma into molecular subgroups (Luminal A, Luminal B, HER2-type, triple negative, and basal-like). READ MORE
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5. TINT Tumor Indicating Normal Tissue : new field of diagnostic biomarkers for prostate cancer
Abstract : Background: Prostate cancer is the most common cancer in Sweden. Due its highly variable behavior, multifocal nature, and insufficient diagnostic methods, prostate cancer is difficult to diagnose and prognosticate. READ MORE