Search for dissertations about: "Multivariate concentric square field"

Showing result 1 - 5 of 7 swedish dissertations containing the words Multivariate concentric square field.

  1. 1. Individual differences in behavior, neurochemistry and pharmacology associated with voluntary alcohol intake

    Author : Shima Momeni; Erika Roman; Bo Söderpalm; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; intermittent access; multivariate concentric square field; open field; risk assessment; risk taking; individual difference; behavior; strain variation; endogenous opioid system; naltrexone; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Alcohol use disorder is a worldwide public health problem and is a disorder with substantial individual variation. There are suggested links between various behavioral traits, comorbid psychiatric diseases and excessive alcohol consumption. READ MORE

  2. 2. Early Environment, Adolescent Alcohol Drinking and Neurobiological Responses to Drugs

    Author : Sara Palm; Ingrid Nylander; Anne-Lie Svensson; Lundblad Martin; Giancarlo Colombo; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescence; beta-endorphin; dopamine; dynorphin; endogenous opioids; enkephalin; high-speed chronoamperometry; housing conditions; maternal separation; multivariate concentric square field™ test; open field test; radioimmunoassay; voluntary alcohol intake; Wistar rats; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Genes and environment interact to determine an individual’s vulnerability or resilience to several psychiatric disorders, including alcohol use disorder (AUD). Alcohol use is often initiated during adolescence and early onset drinking is associated with increased risk for later AUD. READ MORE

  3. 3. Examining Female Resilience to Early Environmental Influences : Short- and long-term consequences on behaviour, HPA axis activity and alcohol intake after prolonged maternal separation

    Author : Stina Lundberg; Erika Roman; Ingrid Nylander; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescence; Adulthood; Corticosterone; Early-life stress; Handling; Maternal deprivation; Multivariate concentric square field; MCSF; Sex differences; Social play behavior; Stress reactivity; Supplier differences; Pharmaceutical Science; Farmaceutisk vetenskap;

    Abstract : Early-life experiences are an important factor influencing further development of the individual. Adverse experiences early in life, such as various kinds of abuse or neglect, are types of early-life stress that can adversely affect an individuals health, as well as contribute to the development of an array of disorders later in life. READ MORE

  4. 4. Adolescent behavior : Links to early-life stress and alcohol in male and female rats

    Author : Stina Lundberg; Erika Roman; Ingrid Nylander; Heidi MB Lesscher; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescence; alcohol exposure; behavior; corticosterone; dynorphin; early life; endogenous opioid peptides; Met-enkephalin-Arg6Phe7 MEAP ; individual differences; multivariate concentric square field MCSF ; phenotyping; radioimmunoassay; selective breeding for alcohol consumption; voluntary alcohol intake; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Adolescence is an important developmental phase with large changes in behavior, physiology and neurobiology, which transform an individual from immature child to independent adult. Due to these changes, adolescence is a sensitive period for exposure to environmental factors such as stress and drug exposure; it is also a common age of onset for alcohol consumption as well as several psychiatric disorders. READ MORE

  5. 5. Cellular Reactions and Behavioral Changes in Focal and Diffuse Traumatic Brain Injury : A Study in the Rat and Mouse

    Author : Sara Ekmark Lewén; Lars Hillered; Niklas Marklund; Anders Lewén; Mårten Risling; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traumatic brain injury; Astrocytes; Inflammatory response; Multivariate concentric square field test; Morris water maze; Exploratory behavior; Risk taking; Functional outcome.; Neurosurgery; Neurokirurgi;

    Abstract : Traumatic brain injury (TBI) is a severe condition and a major cause of death and disability. There is no pharmacological treatment available in clinical practice today and knowledge of brain injury mechanisms is of importance for development of neuroprotective drugs. READ MORE