Search for dissertations about: "Mutant Proteins"
Showing result 21 - 25 of 422 swedish dissertations containing the words Mutant Proteins.
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21. Temperature-inducible and calcium-regulated proteins encoded by the virulence plasmid of Yersinia
Abstract : The pathogenic members of the genus Yersinia, Y. pseudotuberculosis, Y. pestis and Y. enterocolitica are transmitted from animals to man and may give rise to disease with a variety of symptoms. READ MORE
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22. NMR studies of DNA/RNA-binding proteins
Abstract : This thesis concerns the structure and internal dynamics inDNA and RNA-binding proteins. While it has long been known thata proper three-dimensional structure is essential for aprotein's ability to interact with other biomolecules, theinfluence of the inherent protein dynamics is less wellunderstood. READ MORE
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23. The Drosophila POU/Oct factors: multifaceted proteins
Abstract : Dysregulation of physiological and cellular processes underlies various pathological conditions, including cancer and inflammatory disorders. Unraveling the molecular mechanisms driving these processes is crucial. READ MORE
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24. Protein Dynamics Studied by NMR Spin Relaxation. Conformational Transitions of a Calmodulin Mutant
Abstract : Binding of calcium to the protein calmodulin leads to molecular reorganization that enables interaction with target peptides and activation of downstream processes. I have studied the dynamics of the calcium-loaded form of a C-terminal calmodulin mutant (E140Q-Tr2C) using NMR spin relaxation experiments. READ MORE
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25. Methyltransferase Ash1, histone methylation and their impact on Polycomb repression
Abstract : Antagonistic interactions between Polycomb Group (PcG) and Trithorax Group (TrxG) proteins orchestrate the expression of key developmental genes. Distinct maternally loaded repressors establish the silenced state of these genes in cells where they should not be expressed and later PcG proteins sense whether a target gene is inactive and maintain the repression throughout multiple cell divisions. READ MORE