Search for dissertations about: "My Hedhammar"

Showing result 1 - 5 of 8 swedish dissertations containing the words My Hedhammar.

2. 1. Strategies for facilitated protein recovery after recombinant production in Escherichia coli

   Author : My Hedhammar; Sophia Hober; Alois Jungbauer; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ion-exchange chromatography; protein A; Z; Zbasic; Zacid; fusion protein; proteolytic cleavage; immobilised protease; flow cytometry; inclusion bodies; solid-phase refolding; Molecular biology; Molekylärbiologi;

   Abstract : The successful genomic era has resulted in a great demand for efficient production and purification of proteins. The main objective of the work described in this thesis was to develop methods to facilitate recovery of target proteins after recombinant production in Escherichia coli. READ MORE

4. 2. Integrative structural biology of protein fibers: Spider silk and beta-lactoglobulin nanofibrils

   Author : Danilo Hirabae De Oliveira; My Hedhammar; Christofer Lendel; Martin Humenik; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Spider Silk; Spidroin; fiber protein structure; amyloid-like fibers; Beta-lactoglobulin; Spindel silke; Spidroin; fiberproteinstruktur; amyloidliknande fibrer; Betalaktoglobulin; Biotechnology; Bioteknologi;

   Abstract : Proteins found in nature offer a vast range of exceptional materials, including high-performancebiopolymers such as spider silks and whey protein nanofibrils. Fibrous proteins possess immensepotential for developing novel materials suited for various applications, such as medicalbiomaterials or industrial products. READ MORE

5. 3. Modular Hyaluronan-Based Hydrogels for 3D Cell Culture and Bioprinting

   Author : Michael Jury; Daniel Aili; Robert Selegård; My Hedhammar; Linköpings universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Hyaluronan; 3D cell-culture; Biofunctionality; Bioprinting;

   Abstract : Three-dimensional (3D) cell culture facilitates development of biological relevant assays for drug screening and toxicity testing. Compared to conventional 2D cell culture, cells cultured in 3D can more accurately mimic human tissues and organs and thus provide ex vivo data with potentially better predictive value for cancer research, pharmacology, and toxicology, reducing the need for animal models, improving experimental reproducibility, and reducing time and costs in drug development. READ MORE

6. 4. Expanded knowledge on silk assembly for development of bioactive silk coatings

   Author : Linnea Nilebäck; My Hedhammar; Renko de Vries; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Recombinant spider silk; Self-assembly; Biomaterial; Implant coating; Functionalization; Multi-functional; Bioactive; Cell culture scaffold; Antibacterial; Bioteknologi; Biotechnology;

   Abstract : Silk is a fascinating natural material made from proteins that self-assemble through structural rearrangements into one of the toughest materials known. As silk is protein-based, durable and elastic, it has many features that makes it suitable as a scaffold material for tissue engineering. READ MORE

7. 5. Hierarchical Assembly Investigations and Multiscale Characterization of Protein-based Materials : Insights from Whey Protein Nanofibrils and Recombinant Spider Silk Microspheres

   Author : Eirini Ornithopoulou; My Hedhammar; Thomas Crouzier; Christina Divne; Tim Melander Bowden; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hierarchical Assembly; Protein-based materials; Whey Protein Nanofibrils; β-Lactoglobulin; Recombinant Spider Silk; Microspheres; Biomedical Applications; Surface Biofunctionalization; Hierarkisk montering; Proteinbaserade material; Vassleprotein nanofibriller; β-Laktoglobulin; Rekombinant spindelsilke Mikrosfärer; Biomedicinska tillämpningar; Ytbiokonjugering; Biotechnology; Bioteknologi;

   Abstract : Protein-based materials, with their unique properties of combining high strength, while maintaining elasticity, and their inherent biocompatibility, hold immense potential for various applications. In order to harness these properties, we need to understand and control how protein building blocks come together to form hierarchically structured materials. READ MORE