Search for dissertations about: "Mycobacterium tuberculosis"
Showing result 11 - 15 of 109 swedish dissertations containing the words Mycobacterium tuberculosis.
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11. Targeting Mycobacterium tuberculosis Proteins: Structure and Function Studies of Five Essential Proteins
Abstract : This thesis describes the target selection, cloning, expression, purification, crystallization, structure and biochemical characterization of five essential Mycobacterium tuberculosis (Mtb) proteins. The search for drugs against the causal agent of tuberculosis is urgently needed and the targeting of essential genes is necessary to fulfill this goal. READ MORE
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12. Drug-resistant Mycobacterium tuberculosis in Estonia
Abstract : Tuberculosis (TB) infection and disease patterns among different populations are extremely heterogeneous. This thesis explores mainly by microbiological methods the epidemiology of TB in Estonia. Through the work high rates of drug resistance were found. READ MORE
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13. Mycobacterium tuberculosis and the human macrophage : shifting the balance through inflammasome activation
Abstract : Mycobacterium tuberculosis is a very successful pathogen and tuberculosis constitutes a major threat to global health worldwide. The World Health Organization (WHO) estimates that almost nine million new cases and 1. READ MORE
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14. Structural Studies of a Xyloglucan Endotransglycosylase from Populus tremula x tremuloides and Three Conserved Hypothetical Proteins from Mycobacterium tuberculosis
Abstract : This thesis describes the structural studies of four different proteins from two organisms. Xyloglucan endotransglycosylases, XETs, are involved in plant cell wall expansion and remodeling by splitting and reconnecting xyloglucan-cellulose crosslinks. The first crystal structure of a XET enzyme has been determined to 1.8 Å. READ MORE
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15. Molecular Palaeopathology : Ancient DNA analyses of the bacterial diseases tuberculosis and leprosy
Abstract : This thesis “Molecular Palaeopathology. Ancient DNA analyses of the bacterial diseases tuberculosis and leprosy” deals with molecular palaeopathology, i.e. in this case the use of molecular methods to analyse ancient bacterial DNA in order to get further knowledge of diseases in ancient times. READ MORE