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Showing result 1 - 5 of 20 swedish dissertations matching the above criteria.

  2. 1. Invasive and Metastatic Properties of Advanced Prostate Cancer

    Author : Karin Jennbacken; Göteborgs universitet; []
    Keywords : Prostate cancer; Androgen-independent; Castration-resistant; Metastasis; Invasion; Lymphangiogenesis; Cell adhesion; N-cadherin; VEGF-C; MRI;

    Abstract : Prostate cancer is initially androgen-dependent (AD) and therefore androgen deprivation therapy (ADT) is generally used to treat advanced prostate cancer. However, the long-term treatment effects are insufficient and over time an androgen-independent (AI) tumor relapses, which is generally highly aggressive and metastatic. READ MORE

  4. 2. Neuron-glial Interaction in the Developing Peripheral Nervous System

    Author : Mikael Corell; Åsa Fex Svenningsen; Klas Kullander; Helgi Schöith; Heape Anthony; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Schwann cell; nonmyelinating Schwann cell; myelinating Schwann cell; development; proliferation; differentiation; myelin; neural stem cell; central nervous system; peripheral nervous system; enteric nervous system; N-cadherin; GABA; GAD; GABA B receptor; baclofen; CGP55485; Neuroscience; Neurovetenskap; Neuroscience; Neurovetenskap;

    Abstract : The nervous system, including the brain, is the most sophisticated organ in the mammalian body. In such a complex network, neuron-glial interaction is essential and controls most developmental processes, such as stem cell fate determination, migration, differentiation, synapse formation, ensheathment and myelination. READ MORE

  5. 3. The role of N-cadherin and S1P/S1P1 in pancreas development

    Author : Jenny Johansson; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Organogenesis of epithelial organs requires interaction between epithelial and mesenchymal tissues. During pancreas development, mesenchyme-derived structures induce specification, growth and differentiation of pancreatic epithelial cells. READ MORE

  6. 4. Classical cadherins and the thyroid. Studies on organ development and epithelial differentiation

    Author : Mats Grände; Göteborgs universitet; []
    Keywords : Thyroid; cadherin; TGF-; EGF; MEK; development; EMT;

    Abstract : The cadherins are key regulators of tissue patterning and organ formation. E-cadherin is important for cell-cell adhesion and promotes epithelial morphogenesis and maintenance of the epithelial phenotype. READ MORE

  7. 5. Cell adhesion molecules during odontogenesis and tooth-related diseases

    Author : Robert Heymann; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cell adhesion molecules play essential roles in the development and disease of tooth and oral structures, as well as in the maintenance of adult tissue structure/function. It has been shown that different types of cell adhesion molecules (CAMs) play an important part in craniofacial development when ectomesenchymal cells migrate from the neural list to the primitive oral cavity, giving rise to the palatal processes and tooth germs. READ MORE