Search for dissertations about: "N-linked glycosylation"

Showing result 21 - 25 of 35 swedish dissertations containing the words N-linked glycosylation.

  2. 21. Tumor progression in melanocytic lesions : biological and diagnostic implications

    Author : Lena Kanter-Lewensohn; Karolinska Institutet; Karolinska Institutet; []
    Keywords : melanocytic tumors; MIB-1; Bcl-2; IGF-1R. p27; cyclins; cdks and Tamoxifen;

    Abstract : Cutaneous malignant melanoma has an annual incidence of 5% in Sweden, with about 1500 cases diagnosed yearly. In routine histopathology there are diagnostic difficulties in the analysis of pigmented lesions. READ MORE

  4. 22. Structural and evolutionary studies of a lipocalin: the alpha1-microglobulin protein and its gene

    Author : Annika Lindqvist; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; embryology human ; ontogeny; teratology; AMBP; Development biology; protein HC; bikunin; Utvecklingsbiologi; teratologi; embryologi människa ; Genetics; cytogenetics; Genetik; cytogenetik;

    Abstract : a1-microglobulin is a small glycoprotein present in plasma and in tissues surrounding the gastrointestinal and respiratory tracts. a1-microglobulin is a member of the lipocalin protein family and exhibits several of the typical traits of a lipocalin; it binds an unknown ligand which causes the brown color of the protein, it forms complexes with various different proteins and there have been indications of the presence of a receptor for a1-microglobulin on T-lymphocytes. READ MORE

  5. 23. Influenza Neuraminidase : Conserved features of a rapidly mutating virus

    Author : Henrik Östbye; Pia Ädelroth; Anice Lowen; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; influenza; virology; neuraminidase; biokemi; Biochemistry;

    Abstract : Influenza A viruses (IAVs) of the H1N1 and H3N2 serotypes are the major cause of seasonal influenza epidemics. IAVs are labeled based on the antigenic properties of the two surface glycoproteins and main antigens: hemagglutinin (HA/H) and neuraminidase (NA/N). READ MORE

  6. 24. A New Look into Protein C Inhibitor : Posttranslational Modifications and their Functions

    Author : Wei Sun; Sophia Schedin Weiss; Hakon Leffler; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protein C inhibitor; posttranslational modifications; N-glycan; O-glycan; mass spectrometry; factor Xa; thrombin; prostate specific antigen; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Abstract : The influences of posttranslational modifications on the functions of the versatile serpin protein C inhibitor (PCI) were studied. PCI is a serine protease inhibitor that is expressed in many tissues and secreted to various fluids in human, including blood plasma, seminal plasma, and urine. READ MORE

  7. 25. Transmembrane helices : tails, turns and snorkels

    Author : Magnus Monné; Donald Engelman; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Abstract : The assembly and structure of membrane proteins are intimately related. Targeting and insertion of membrane proteins into the endoplasmatic reticulum (ER) membrane involve many components that facilitate the folding of the native structure. READ MORE