Search for dissertations about: "NA assembly"

Showing result 1 - 5 of 9 swedish dissertations containing the words NA assembly.

  1. 1. Influenza neuraminidase assembly : Evolution of domain cooperativity

    Author : Diogo da Silveira Vieira da Silva; Robert Daniels; Ron Fouchier; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Influenza; neuraminidase; assembly; transmembrane domain; evolution; Biochemistry; biokemi;

    Abstract : Influenza A virus (IAV) is one of the most common viruses circulating in the human population and is responsible for seasonal epidemics that affect millions of individuals worldwide. The need to develop new drugs and vaccines against IAVs led scientists to study the main IAV surface antigens hemagglutinin (HA) and neuraminidase (NA). READ MORE

  2. 2. NA transmembrane domain : Amphiphilic drift to accommodate two functions

    Author : Johan Nordholm; Robert Daniels; Ervin Fodor; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; influenza; IAV; neuraminidase; NA; transmembrane domain; TMD; secretory protein; ER-targeting sequence; ER-targeting sequence coding region; protein regulation; NS1; GALLEX; Biochemistry; biokemi;

    Abstract : Neuraminidase (NA) is one of two major antigens on the surface of influenza A viruses. It is comprised of a single N-terminal transmembrane domain (TMD), a stalk domain, and a C-terminal enzymatic head domain that cleaves sialic acid, most notably to release new particles from the host cell surface. READ MORE

  3. 3. Influenza A Virus : Spatial analysis of influenza genome trafficking and the evolution of the neuraminidase protein

    Author : Dan Dou; Robert Daniels; Martin Schwemmle; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Influenza A virus; IAV; neuraminidase; NA; IAV genome trafficking; viral entry; viral replication; co-infection; antigenic drift; antigenic shift; NA assembly; transmembrane domain; evolution; Biochemistry; biokemi;

    Abstract : Influenza A viruses (IAVs) are a common infectious agent that seasonally circulates within the human population that causes mild to severe acute respiratory infections. The severity of the infection is often related to how the virus has evolved with respect to the pre-existing immunity in the population. READ MORE

  4. 4. Templating and self-assembly of biomimetic materials

    Author : Christian Mille; Lennart Bergström; Mika Linden; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; biomimetic; biotemplating; self-assembly; triply periodic minimal surfaces; the gyroid; photonic crystals; band gap; structural color; chirality; butterflies; membrane proteins; lipid bilayers; sol-gel; mesostructured; polyhedral nanofoams; Materials Chemistry; materialkemi;

    Abstract : This thesis focuses on the use of biomolecular assemblies for creating materials with novel properties. Several aspects of biomimetic materials have been investigated, from fundamental studies on membrane shaping molecules to the integration of biomolecules with inorganic materials. READ MORE

  5. 5. Filament assembly and structural studies of intermediate filament like protein, FilP, in Streptomyces coelicolor

    Author : Ala Javadi; Linda Sandblad; Martin Thanbichler; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Cytoskeleton; Intermediate filament-like; FilP; Streptomyces coelicolor; filament assembly; cryoelectron tomography; single particle analysis; crystallography; cellulose affinity;

    Abstract : The cytoskeleton, known as intracellular connected filaments, has a prominent role in cellular behavior, motility, and stability. The following three major types of polymers have been characterized as cytoskeleton in eukaryotes: microtubules that are 25 nm in diameter, actin filaments that are 7 nm in diameter, and intermediate filaments (IF) that are 10 nm in diameter. READ MORE