Search for dissertations about: "NA"

Showing result 1 - 5 of 732 swedish dissertations containing the word NA.

  2. 1. NA transmembrane domain : Amphiphilic drift to accommodate two functions

    Author : Johan Nordholm; Robert Daniels; Ervin Fodor; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; influenza; IAV; neuraminidase; NA; transmembrane domain; TMD; secretory protein; ER-targeting sequence; ER-targeting sequence coding region; protein regulation; NS1; GALLEX; Biochemistry; biokemi;

    Abstract : Neuraminidase (NA) is one of two major antigens on the surface of influenza A viruses. It is comprised of a single N-terminal transmembrane domain (TMD), a stalk domain, and a C-terminal enzymatic head domain that cleaves sialic acid, most notably to release new particles from the host cell surface. READ MORE

  4. 2. Studies on inhibitory modulation of urinary tract motility

    Author : Na Guan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Overactive Bladder (OAB) is a symptom syndrome characterized by urgency and frequency, with or without urge incontinence. Research concerning the mechanisms underlying OAB and finding new inhibitory factor(s) is intensive. READ MORE

  5. 3. HOST EPIGENETIC REGULATOR BMI1 AND VIRAL FIBER PROTEIN FOR EQUILIBRIUM BETWEEN ADENOVIRUS AND HOST

    Author : Manli Na; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; BMI1; Dual-gene expression; Epigenetic; Equilibrium; Fiber; HSC; HDAC; TSA;

    Abstract : Human adenoviruses (Ads) are broadly used in cancer gene therapy, vaccine development and gene delivery. The modified Ad5 or Ad2 viruses have been successfully used as oncolytic agents in pre-clinical studies. However they could not be translated into clinic utility due to a number of limitations including inefficient Ad spread among tumor cells. READ MORE

  6. 4. Frequency Domain Linearized Navier-Stokes Equations Methodology for Aero-Acoustic and Thermoacoustic Simulations

    Author : Wei Na; Gunilla Efraimsson; Susann Boij; Martinez Lera Paula; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Linearized Navier-Stokes Equations; frequency domain; fluid equivalent model; hybrid liner; thermoacoustic instabilities; Rijke-tube; Engineering Mechanics; Teknisk mekanik;

    Abstract : The first part of the thesis focuses on developing a numerical methodology to simulate the acoustic properties of a hybrid liner consisting of a perforated plate, a porous layer and a Helmholtz cavity. Liners are always a standard way to reduce noise in today’s aeroengines, e.g. READ MORE

  7. 5. Telomerase activation and its clinical implications in human thyroid tumors

    Author : Na Wang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Telomerase is a ribonucleoprotein enzyme. The catalytic and rate-limiting component of telomerase is referred to as telomerase reverse transcriptase (TERT) that plays an important role in telomere maintenance, cell immortalization and malignant transformation. READ MORE