Search for dissertations about: "NAFLD"

Showing result 1 - 5 of 15 swedish dissertations containing the word NAFLD.

  1. 1. Liver-related complications and metabolic comorbidities during long-term follow-up of patients with Non-Alcoholic Fatty Liver Disease

    University dissertation from Lund University: Faculty of Medicine

    Author : Kristina Önnerhag; [2019]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic kidney disease CKD ; Epidemiology; Fibrosis; Hepatocellular cancer; Insulin resistance; Liver cirrhosis; Metabolic syndrome; NAFLD; NASH; Non-alcoholic fatty liver disease; non-alcoholic steatohepatitis;

    Abstract : Background: Non-alcoholic fatty liver disease (NAFLD) is highly associated with the metabolic syndrome, and due to increasing prevalence of for example obesity it is now the most common liver disease in the world. A minority progress to advanced fibrosis/cirrhosis, which is associated with increased mortality, but it is not entirely clear which patients who have an increased risk of fibrosis. READ MORE

  2. 2. Genetic variants for liver fat accumulation and circulating triglyceride levels

    University dissertation from Diabetes and cardiovascular disease - genetic epidemiology

    Author : Ivana Stojkovic; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NAFLD; genetic variations; triglycerides; ALAT; dietary intake; type 2 diabetes; cardiovascular disease;

    Abstract : Non-alcoholic fatty liver disease (NAFLD), obesity and type 2 diabetes(T2D) are strongly associated and today their prevalence reaches epidemic proportions. NAFLD has a multi-factorial aetiology, both genetic and environmental factors are equally important. READ MORE

  3. 3. Protein kinase STK25 is a regulator of hepatic lipid partitioning and whole body metabolism

    University dissertation from Diabetes and cardiovascular disease - genetic epidemiology

    Author : Manoj Amrutkar; Göteborgs universitet.; Gothenburg University.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NAFLD; NASH; Liver lipid metabolism; Type 2 diabetes; STK25;

    Abstract : In past decade, type 2 diabetes (T2D) and associated metabolic complications have become a major global threat for human health with epidemic increase in incidence. Currently available treatments for T2D have several limitations and side effects making it difficult safely reach adequate metabolic control. READ MORE

  4. 4. Susceptibility to chronic liver disease

    University dissertation from Diabetes and cardiovascular disease - genetic epidemiology

    Author : Maria Antonella Burza; Göteborgs universitet.; Gothenburg University.; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic liver disease; susceptibility; human genetics; NAFLD; ALD; PNPLA3;

    Abstract : The onset and the progression of chronic liver disease involve environmental and genetic factors. Hepatic stellate cells (HSCs) are important players in these processes and are the main storage site for retinol. READ MORE

  5. 5. Metabolic and endocrine effects of SGLT2 inhibition

    University dissertation from Diabetes and cardiovascular disease - genetic epidemiology

    Author : Per Lundkvist; Jan Eriksson; Lars Lind; Maria J Pereira; Michael Alvarsson; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SGLT2 inhibition; GLP-1 receptor agonism; DPP4 inhibition; NAFLD; prediabetes; type 2 diabetes; obesity; metabolic syndrome; glucagon.; Medicinsk vetenskap; Medical Science;

    Abstract : Obesity and type 2 diabetes (T2D) are two growing global health problems with similar comorbidity profiles. SGLT2 inhibitors (SGLT2i) improve blood glucose control and can relieve both T2D and obesity, as well as their associated health problems such as hypertension, kidney failure, and cardiovascular disease. READ MORE