Search for dissertations about: "NATURAL SCIENCES Biology"

Showing result 21 - 25 of 3375 swedish dissertations containing the words NATURAL SCIENCES Biology.

  1. 21. Studies on the Role of Apoptosis in Kidney Diseases

    University dissertation from KTH Royal Institute of Technology

    Author : Linnéa Nilsson; KTH.; [2019]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apoptosis; diabetic kidney disease; hyperglycemia; mesangial cells; microscopy; ouabain; podocytes; proximal tubule cells; RNA-seq; SGLT; Apoptos; diabetisk njursjukdom; hyperglykemi; mesangiala celler; mikroskopi; ouabain; podocyter; proximala tubuli celler; RNA-seq; SGLT; Biologisk fysik; Biological Physics;

    Abstract : Apoptosis is one of the most common types of cell death. Under physiological conditions, it plays an essential role in removal of damaged and potentially harmful cells. Excessive apoptosis has however been linked to a number of diseases including proteinuric kidney disease and DKD, and is believed to enhance the disease progression. READ MORE

  2. 22. Thiopurine S-methyltransferase - characterization of variants and ligand binding

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Annica Blissing; Linköpings universitet.; Linköpings universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Thiopurine S-methyltransferase TPMT ; protein stability; enzyme kinetics; ligand binding; isothermal titration calorimetry ITC ; 8-anilinonaphthalene-1-sulfonic acid ANS ;

    Abstract : Thiopurine S-methyltransferase (TPMT) belongs to the Class I S-adenosylmethionine-dependent methyltransferase (SAM-MT) super family of structurally related proteins. Common to the members of this large protein family is the catalysis of methylation reactions using S-adenosylmethionine (SAM) as a methyl group donor, although SAM-MTs act on a wide range of different substrates and carry out numerous biologically important functions. READ MORE

  3. 23. Evolution of acetylcholine receptors and study of the anatomy of the mouse brain reward system

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Julia Pedersen; Dan Larhammar; Arnaud Chatonnet; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Ventral Tegmental Area; Mesocorticolimbic system; Glutamate; Optogenetics; Histology; Acetylcholine; Receptor; Muscarininc; Nicotinic; G protein-coupled receptor; Gene duplication; Tetraploidization; Synteny; Paralogon; Ohnolog; Zebrafish; Spotted gar; Neuroscience; Neurovetenskap;

    Abstract : This thesis work is divided in two parts. In the first part, I make use of the transgenic TRPV1-Cre mouse line as a tool to investigate the midbrain ventral tegmental area (VTA). READ MORE

  4. 24. Regulatory programs controlling profileration during Drosophila nervous system development

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Erika Gunnar; Linköpings universitet.; Linköpings universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The central nervous system (CNS) is the most complex organ in the body, responsible for complex functions, including thinking, reasoning and memory. The CNS contains cells of many different types, often generated in vast numbers. READ MORE

  5. 25. Hybrid zone dynamics, assortative mating, and migratory programmes in a willow warbler migratory divide

    University dissertation from Lund, Sweden : Lund University

    Author : Keith W. Larson; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; migratory divide; phenotype; willow warbler; hybrid zone; tension zone; Phylloscopus trochilus; migratype; assortative mating; migration; biology; biologi; evolutionär genetik; evolutionary genetics;

    Abstract : In this thesis I will compare and contrast the two willow warbler subspecies (Phylloscopus trochilus trochilus and P. t. acredula) with differing migratory phenotypes (or "migratype") in the context of their migratory divide and hybrid zone in central Sweden. Their migratory programs differ in the direction and distance traveled during migration. READ MORE