Search for dissertations about: "NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi"
Showing result 6 - 10 of 45 swedish dissertations containing the words NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi.
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6. Genetic pathways controlling CNS development : The role of Notch signaling in regulating daughter cell proliferation in Drosophila
Abstract : The human central nervous system (CNS) displays the greatest cellular diversity of any organ system, consisting of billions of neurons, of numerous cell sub-types, interconnected in a vast network. Given this enormous complexity, decoding the genetic programs controlling the multistep process of CNS development remains a major challenge. READ MORE
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7. Aspects of inflammation, angiogenesis and coagulation in preeclampsia
Abstract : Preeclampsia is a major challenge to obstetricians, due to its impact on maternal and fetal morbidity and mortality and the lack of preventive and treatment strategies. The overall aim of this thesis is to increase the knowledge of the pathogenesis of preeclampsia including the role of inflammation, angiogenesis and coagulation, both locally at the fetomaternal interface and in the maternal circulation. READ MORE
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8. Glutamate and GABA signalling components in the human brain and in immune cells
Abstract : Glutamate and γ-aminobutyric acid (GABA) are the principal excitatory and inhibitory neurotransmitters in the central nervous system (CNS). They both can activate their ionotropic and metabotropic receptors. READ MORE
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9. Adenovirus for Cancer Therapy : With a Focus on its Surface Modification
Abstract : Adenovirus serotype 5 (Ad5) is widely used as an oncolytic agent for cancer therapy. However, its infectivity is highly dependent on the expression level of coxsackievirus-adenovirus receptor (CAR) on the surface of tumor cells. READ MORE
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10. Vascular targeting for enhanced cancer immunotherapy
Abstract : Induced angiogenesis and chronic inflammation are major components of tumor immunosuppression. The scope of this thesis is to understand the role of the vasculature in anti-tumor immunity and thereby to improve cancer immunotherapy. READ MORE