Search for dissertations about: "NATURVETENSKAP Kemi Biokemi Molekylärbiologi"
Showing result 11 - 15 of 225 swedish dissertations containing the words NATURVETENSKAP Kemi Biokemi Molekylärbiologi.
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11. NMR studies on interactions between the amyloid β peptide and selected molecules
Abstract : Alzheimer’s disease is an incurable neurodegenerative disorder linked to the amyloid β (Aβ) peptide, a 38-43 residue peptide. The detailed molecular disease mechanism(s) is (are) unknown, but oligomeric Aβ structures are proposed to be involved. READ MORE
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12. Design of Glutathione Transferase Variants for Novel Activities with Alternative Substrates
Abstract : Glutathione transferases (GSTs) play a pivotal role in cellular defense, since they are main contributors to the inactivation of genotoxic compounds of exogenous and endogenous origins. Directed evolution was used to improve the catalytic activities of Theta class GST T1-1 toward different substrates. READ MORE
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13. Quantum dot biomarkers for tracking endothelial progenitor cells and activated endothelium
Abstract : The development of new visualization techniques is essential in the field of bioimaging to gain deeper knowledge about various medical and biological events at the cellular and molecular levels. Quantum dots (QDs) are semiconductor nanocrystals which are opening new perspectives in biotechnology due to their powerful optical properties and high stability. READ MORE
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14. Prediction of zinc-binding sites in proteins and efficient protein structure description and comparison
Abstract : A large number of proteins require certain metals to stabilize their structures or to function properly. About one third of all proteins in the Protein Data Bank (PDB) contain metals and it is estimated that approximately the same proportion of all proteins are metalloproteins. READ MORE
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15. Unveiling Mechanistic Details of Macromolecular Interactions: Structural Design and Molecular Modelling of DNA-Protein Systems in Their Active State
Abstract : Molecular structure is fundamental for understanding mechanisms of molecular interactions. This applies not least to understanding biological function: every biological cell, whether bacterial or human, is an immensely complex system of thousands of molecules that exist in constant motion and interaction with each other. READ MORE