Search for dissertations about: "NATURVETENSKAP Kemi Biokemi"

Showing result 11 - 15 of 317 swedish dissertations containing the words NATURVETENSKAP Kemi Biokemi.

  2. 11. Computational Protein Evolution : Modeling the Selectivity and Promiscuity of Engineered Enzymes

    Author : Klaudia Szeler; Shina C. Lynn Kamerlin; Mikael Widersten; Maria Ramos; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; enzymes; kinetics; catalysis; density functional theory; empirical valence bond; diesters; evolution; promiscuity; Biokemi; Biochemistry;

    Abstract : Enzymes are biological catalysts that significantly increase the rate of all biochemical reactions that take place within cells and are essential to maintain life. Many questions regarding their function remain unknown. READ MORE

  4. 12. NMR studies on interactions between the amyloid β peptide and selected molecules

    Author : Anna Wahlström; Astrid Gräslund; Göran Karlsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Amyloid β peptide; Alzheimer s disease; Aggregation; Oligomer; Amyloid; Interaction; Nuclear Magnetic Resonance Spectroscopy; Circular Dichroism Spectroscopy; Thioflavin T; Detergent; Congo red; Affibody; Cyclodextrin dimer; Metal ion; Chemistry; Kemi; Biochemistry; Biokemi; Biophysics; biofysik;

    Abstract : Alzheimer’s disease is an incurable neurodegenerative disorder linked to the amyloid β (Aβ) peptide, a 38-43 residue peptide. The detailed molecular disease mechanism(s) is (are) unknown, but oligomeric Aβ structures are proposed to be involved. READ MORE

  5. 13. Design of Glutathione Transferase Variants for Novel Activities with Alternative Substrates

    Author : Abeer Shokeer; Bengt Mannervik; Francoise Raffalli-Mathieu; David Josephy; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Organic chemistry; Organisk kemi; Biokemi; Biochemistry; Organisk kemi; Organic Chemistry;

    Abstract : Glutathione transferases (GSTs) play a pivotal role in cellular defense, since they are main contributors to the inactivation of genotoxic compounds of exogenous and endogenous origins. Directed evolution was used to improve the catalytic activities of Theta class GST T1-1 toward different substrates. READ MORE

  6. 14. NMR studies of protein dynamics and structure

    Author : Jörgen Ådén; Magnus Wolf-Watz; Michael Sattler; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NMR; protein dynamics; relaxation; protein folding; Biochemistry; Biokemi; Biophysical chemistry; Biofysikalisk kemi; biokemi; Biochemistry; fysikalisk kemi; Physical Chemistry;

    Abstract : Enzymes are extraordinary molecules that can accelerate chemical reactions by several orders of magnitude. With recent advancements in structural biology together with classical enzymology the mechanism of many enzymes has become understood at the molecular level. READ MORE

  7. 15. Quantum dot biomarkers for tracking endothelial progenitor cells and activated endothelium

    Author : Mátyás Molnár; Ying Fu; Sotirios Karathanasis; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; quantum dots; bioimaging; endothelium; adult stem cells; confocal microscopy; Biologi; Biology; Kemi; Chemistry; Fysik; Physics; Biochemistry;

    Abstract : The development of new visualization techniques is essential in the field of bioimaging to gain deeper knowledge about various medical and biological events at the cellular and molecular levels. Quantum dots (QDs) are semiconductor nanocrystals which are opening new perspectives in biotechnology due to their powerful optical properties and high stability. READ MORE