Search for dissertations about: "NC4 domain"

Found 2 swedish dissertations containing the words NC4 domain.

  2. 1. Cartilage destruction - Release of type IX collagen in joint disease

    Author : Mikael Danfelter; Reumatologi och molekylär skelettbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cartilage destruction; matrix metalloproteinase 13; ECM; assay; neoepitope; NC4 domain; Type IX collagen; fragment;

    Abstract : Cartilage is of vital importance for the function of joints. It is characterized by a prominent extracellular matrix (ECM) that is produced and maintained by relatively few cells of one type, the chondrocyte. READ MORE

  4. 2. Interactions between extracellular matrix proteins and the complement system - In the perspective of cartilage degradation in inflammatory joint diseases

    Author : Camilla Melin Fürst; Malmö Proteinkemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complement system; rheumatoid arthritis; osteoarthritis; extracellular matrix; cartilage degradation; mass spectrometry;

    Abstract : Abstract: The joint diseases osteoarthritis and rheumatoid arthritis are characterized by destructive inflammatory processes that result in pathological changes of the joint tissues, including proteolytic degradation of cartilage and release of extracellular matrix proteins or fragments to the synovial fluid. The complement system, which is a part of the innate immune system, plays a central role in promoting the joint inflammation in these diseases. READ MORE