Search for dissertations about: "NDST1"
Showing result 1 - 5 of 9 swedish dissertations containing the word NDST1.
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1. Role of Heparan Sulfate N-sulfation in Mouse Embryonic Development
Abstract : Heparan sulfate (HS) is a sulfated glycosaminoglycan expressed by all cells in the body. It is found at the cell surface and in the extracellular matrix where it binds a large amount of various ligands including growth factors and morphogens. READ MORE
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2. Heparan Sulfate Proteoglycans in Brain Tumor Development
Abstract : Malignant brain tumors are aggressive neoplasms that remain challenging to treat in spite of their detailed molecular characterization. Both adults and children may suffer from brain tumors, which, if not lethal, can cause severe long-term and devastating side effects. READ MORE
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3. Heparan Sulfate and Development : A Study of NDST Deficient Mice and Embryonic Stem Cells
Abstract : Heparan sulfate (HS) proteoglycans consist of sulfated HS chains covalently bound to core proteins. They are ubiquitously expressed, on the cell surface and in the extracellular matrix, throughout the body. READ MORE
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4. N-Sulfation and Polymerization in Heparan Sulfate Biosynthesis
Abstract : Heparan sulfate (HS) is a glycosaminoglycan present in all cell types covalently attached to core proteins forming proteoglycans. HS interacts with different proteins and thereby affects a variety of processes. READ MORE
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5. Functions of Heparan Sulfate During Mouse Development : Studies of Mice with Genetically Altered Heparan Sulfate Biosynthesis
Abstract : Heparan sulfate (HS) is a ubiquitous polysaccharide on the cell surface and in the extracellular matrix. HS is an important actor in the regulation of cell signaling, especially in the developing embryo. READ MORE