Search for dissertations about: "NF-κB"

Showing result 1 - 5 of 93 swedish dissertations containing the word NF-κB.

  1. 1. Regulation of NF-κB by Calmodulin

    Author : Åsa Antonsson; Thomas Grundström; Ylva Engström; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; NF-κB; calmodulin; transcription; calcium; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Cells experience numerous external signals which they must respond to. Such signals arriving at the cell surface are transduced via various signal transduction pathways and often ultimately result in regulation of transcription. READ MORE

  2. 2. Neuroinflammation in Alzheimer's disease : Focus on NF-κB and C/EBP transcription factors

    Author : Veronica Ramberg; Kerstin Iverfeldt; Josep Saura; Stockholms universitet; []
    Keywords : Alzheimer’s disease; neuroinflammation; NF-κB; C EBP; apoptosis; caspases; FRET; neurokemi och neurotoxikologi; Neurochemistry and Neurotoxicology;

    Abstract : Alzheimer's disease (AD) is the most common form of dementia among elderly. The disease is characterized by amyloid-β (Aβ) plaques, neurofibrillary tangles, loss of synapses and neurons and chronic neuroinflammation. READ MORE

  3. 3. MEKK-1 and NF-κB Signaling in Pancreatic Islet Cell Death

    Author : Dariush Mokhtari; Nils Welsh; Michael Welsh; Anders Tengholm; Shanta Persaud; Uppsala universitet; []
    Keywords : Cell biology; MEKK-1; JNK; human islets; β-cells; siRNA; apoptosis; cell death; MAPK; nitric oxide; cytokines; streptozotocin; c-Rel; NF-κB; Cellbiologi;

    Abstract : Type 1 diabetes is an autoimmune disease resulting in the selective destruction of the insulin producing β-cells in the pancreas. Pro-inflammatory cytokines and the free radical nitric oxide (NO) have been implicated in mediating the destruction of β-cells, possibly through activation of the mitogen activated protein kinases (MAPKs) JNK, ERK and p38. READ MORE

  4. 4. Regulation of activation of NF-κB by Calmodulin in T-lymphocytes

    Author : Sreenivasa Rao Oruganti; Thomas Grundström; Eva Sverinson; Umeå universitet; []
    Keywords : Calcium; Calmodulin; CaMKII; TCR; Bcl10; NF-κB;

    Abstract : Nuclear factor kappa B (NF-kB) is a widely expressed family of transcription factors that are involved in a diverse number of processes. These include inflammation or differentiation, survival or apoptosis, and proliferation or cell cycle arrest. READ MORE

  5. 5. Characterization and environmental influences on inflammatory and physiological responses

    Author : Hazem Khalaf; Per-Erik Olsson; Joe de Pierre; Örebro universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; Inflammation; NF-κB; cytokines; pharmaceuticals; zebrafish; Biology; Biologi; NATURAL SCIENCES; NATURVETENSKAP; Biology; Biologi;

    Abstract : Pharmaceuticals are regularly released into the environment, in particular nonsteroidalanti-inflammatory drugs (NSAIDs) and antibiotics. The measuredconcentrations are relatively low and have therefore been considered to be harmless. READ MORE