Search for dissertations about: "NF-Y"

Showing result 1 - 5 of 13 swedish dissertations containing the word NF-Y.

  1. 1. Regulation of the platelet-derived growth factor β-receptor

    Author : Catrin Molander; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGF; inflammation; TNF-a; tyrosine kinase; medulloblastoma; Myc; NF-Y; Sp1;

    Abstract : Growth factors are important signalling molecules, regulating cell growth, as well as cell movement, differentiation and apoptosis. They bind to specific receptors on the cell surface causing activation of the receptors. Activated receptors then attract adaptor molecules that brings the signal further into the cell. READ MORE

  2. 2. Transcriptional Regulation ofthe Platelet-Derived Growth Factor beta-receptor

    Author : Anders Hackzell; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : PDGF; cell cycle; p73; p53; SV40; NF-Y; Sp1; Myc;

    Abstract : The Platelet Derived-Growth Factor (PDGF) receptors and ligands are expressed in cells of predominantly mesenchymal origin. Binding of the ligands to the receptors stimulates cell proliferation and other cellular responses such as differentiation and cell movement. READ MORE

  3. 3. Regulation of the Epstein-Barr virus C promoter by the OriP-EBNA1 complex

    Author : Cecilia Boreström; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Epstein-Barr virus; EBNA1; NF-Y; Sp1; Oct-2; Bright; E2F1; transcriptional regulation; Cp; oriP;

    Abstract : Epstein-Barr Virus (EBV) is an exclusively human, lymphotropic herpes virus that infects more than 90% of the population worldwide. Primary infection usually occurs during the early years of life and does not result in any recognized disease. READ MORE

  4. 4. Studies on the regulatory roles of cholesterol and bile acids

    Author : Charlotte Murphy; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Cholesterol; cholic acid; bile acids; cholesterol homeostasis; squalene epoxidase; mevalonate kinase; cob I alamin adenotransferase; SREBP; NF-Y;

    Abstract : Cholesterol is essential for normal growth and development in mammals. However, excess cholesterol can be harmful leading to diseases such as atherosclerosis and gallstones. Once formed the ring structure of cholesterol cannot be catabolised by the body and must therefore be converted to other compounds for excretion. READ MORE

  5. 5. Purification of general RNA polymerase II transcription factors from mouse for studies of proliferation-specific transcription

    Author : Irina Kotova; Lars-Gunnar Larsson; Umeå universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Genetik; Genetics; Genetik;

    Abstract : Accurate initiation of transcription by RNA polymerase II depends on general transcription factors (GTFs), which include the TATA-binding protein (TBP) and the transcription factors (TF) IIB, IIF, IIE and IIH. In order to reconstitute mouse transcription in vitro, we cloned the genes encoding mouse TFIIB, and both subunits of TFIIE and TFIIF from a mouse cDNA library. READ MORE