Search for dissertations about: "NFIB"

Found 2 swedish dissertations containing the word NFIB.

  1. 1. Transcriptomic and functional studies of fusion oncogene-driven salivary gland tumors

    Author : Maryam K. Afshari; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; fusion oncogene; MYB; NFIB; PLAG1; HMGA2; adenoid cystic carcinoma; pleomorphic adenoma; targeted therapy;

    Abstract : Fusion genes are potent oncogenic drivers resulting from exchange of regulatory/coding sequences between two genes. They were originally identified in leukemias but are now recognized as key oncogenic events also in many solid tumors, including salivary gland tumors (SGTs). READ MORE

  2. 2. Studies of gene fusions and copy number alterations in salivary and adnexal neoplasms

    Author : Marta Persson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : cancer genetics; fusion oncogenes; chromosome translocation; MYB; NFIB; CRTC1; MAML2; salivary gland; breast; adenoid cystic carcinoma; mucoepidermoid carcinoma; hidradenoma;

    Abstract : Cancer is a genetic disease caused by the accumulation of genetic changes such as mutations and chromosomal rearrangements. An increasing number of genetic studies of both hematological and solid neoplasms have shown that recurrent chromosome translocations often result in fusion oncogenes. READ MORE