Search for dissertations about: "NGS"

Showing result 16 - 20 of 73 swedish dissertations containing the word NGS.

  2. 16. Beyond GWAS : Novel Methods and Resources for Genetic Epidemiology

    Author : Daniel Schmitz; Åsa Johansson; Tuuli Lappalainen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; GWAS; NGS; long-read sequencing; mendelian randomization; WGS; CNVs;

    Abstract : Since the first human genome assembly’s release, our knowledge of the genetic architecture of complex traits and diseases has grown steadily. Genome-wide association studies (GWAS) played a major role but are limited to common traits and single-nucleotide polymorphisms (SNPs). READ MORE

  4. 17. Contributions to the understanding of diversity and evolution in the genus Coreomyces

    Author : Henrik Sundberg; Stefan Ekman; Åsa Kruys; Donald H. Pfister; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ascomycetes; Coreomyces; Corixidae. DNA; DNA extraction; Fungi; ge-nome; host specificity; Laboulbeniales; mating types; MAT-loci; meth-odology; NGS; parasite; position specificity; systematics; taxonomy; Biology with specialization in Systematics; Biologi med inriktning mot systematik; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

    Abstract : The Laboulbeniales is an order of enigmatic ascomycete fungi that are obligate microscopic parasites of arthropods, which are usually non-detrimental. They typically display a high degree of host specificity, and the genus Coreomyces, which is the recurring theme of this thesis, is no exception. READ MORE

  5. 18. Lung Metastases - Diagnostic, Prognostic and Molecular Aspects with Focus on Colorectal Cancer

    Author : Halla Vidarsdottir; Förbättrad diagnostik och prognostik vid lungcancer och metastaser till lunga; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lung cancer; lung metastasis; tissue microarray; TTF-1; napsin A; cytokeratin; GATA3; CDX2; PAX8; CRC; pulmonary metastasectomy; RBM3; recurrence; survival; NGS; Trusight tumor 26; Trusight Oncology 500;

    Abstract : In Sweden 4200 patients are diagnosed with lung cancer and 6500 patients with colorectal cancer (CRC) annually. The lungs are a common site for metastases. Immunohistochemistry (IHC) is a helpful aid in diagnostics of a pulmonary tumour. READ MORE

  6. 19. NGS based studies on primary immunodeficiencies (PIDs) : causative gene identification, tool development and application

    Author : Mingyan Fang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Primary immunodeficiency diseases (PIDs) are composed by a group of highly heterogeneous immune system diseases, of which approximately 350 forms of PID have been described so far. The causative gene of around 60% of patients with PIDs has yet unknown. READ MORE

  7. 20. Undifferenced GPS for Deformation Monitoring

    Author : Johan Vium Andersson; Lars Sjöberg; Jonas Ågren; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; : deformation monitoring; GPS; modified NGS-parameters; undifferenced GPS-observations; Kalman filter; Geoengineering; Geoteknik;

    Abstract : This thesis contains the development of a deformation monitoring software based on undifferenced GPS observations. Software like this can be used in alarm systems placed in areas where the earth is unstable. READ MORE