Search for dissertations about: "NK CD19"

Showing result 1 - 5 of 7 swedish dissertations containing the words NK CD19.

  2. 1. Genetic studies of familial hemophagocytic lymphohistiocytosis

    Author : Kim Göransdotter Ericson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Familial hemophagocytic lymphohistiocytosis FHL ; PRF1 gene; MUNC13-4 gene; NK cells; cytotoxic T lymphocytes;

    Abstract : The main contribution from this thesis is a refined knowledge of locus heterogeneity in familial hernophagocytic lympbohistiocytosis (FHL) and a further characterization of corresponding clinical and immunological phenotypes. Familial hemophagocytic lymphohistiocytosis is a fatal autosomal recessive immune deficiency clinically characterized by fever, cytopenia, hepatosplenomegaly, and hemophagocytosis. READ MORE

  4. 2. What’s in a name? : Sub-fractionation of common lymphoid progenitors

    Author : Sasan Zandi; Mikael Sigvardsson; Avinash Bhandoola; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The hematopoietic system is a highly dynamic organ developed in many multi-cellular organisms to provide oxygen, prevent bleeding and to protect against microorganisms. The blood consist of many different specialized cells that all derive from rare hematopoietic stem cells (HSCs) located in the bone marrow in mice and humans. READ MORE

  5. 3. Immune Changes in Pregnancy : A Survey of some Immunological Variables in Normal and Complicated Pregnancies

    Author : Leif Skamris Matthiesen; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The maternal systemic immune response during pregnancy is only fragmentarily understood. An adequate immune response to the gestational product is of vital importance for a successful pregnancy. READ MORE

  6. 4. The importance of psychological and physical stressors on diabetes-related immunity in a young population – an interdisciplinary approach

    Author : Emma Carlsson; Maria Faresjö; Arne Gerdner; Anneli Frostell; Kristina Lejon; Jönköping University; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; psychological stressors; physical stressors; cellular immune system; type 1 diabetes; young population;

    Abstract : Background: The prevalence of immunological disorders such as type 1 diabetes (T1D) is increasingly common amongst children, adolescents and young adults. There is also an increase in psychosomatic symptoms (depression, insomnia, anxiety, headaches and fatigue etc. READ MORE

  7. 5. Evaluating antitumoral lymphocytes for adoptive cell therapy : oxidative stress, neoantigen processing and co-stimulation

    Author : Stefanie Marie Renken; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rapid advancement in the field of immunotherapy has changed the treatment landscape of cancer, especially with the approval of immune checkpoint inhibitors for a wide range of cancer types. However, a large proportion of patients does not benefit from this treatment. READ MORE