Search for dissertations about: "NK cell education"

Showing result 1 - 5 of 19 swedish dissertations containing the words NK cell education.

  2. 1. NK Cell Cytotoxicity at the Single Cell Level

    Author : Ludwig Brandt; Björn Önfelt; Fredrik Bergh Thorén; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biological Physics; Biologisk fysik;

    Abstract : Natural killer (NK) cells are innate immune cells with the ability to recognize and eliminate virally infected cells and cancer cells without prior sensitization. There is a functional heterogeneity between individual NK cells, where some NK cells are more efficient at killing cancer cells than others. READ MORE

  4. 2. NK cell education and adhesion molecules : implications for immunotherapy

    Author : Arnika Kathleen Wagner; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : NK cells have a key role in immune surveillance. They detect aberrant expression of stressinduced molecules and MHC class I molecules with an array of activating and inhibitory receptors. READ MORE

  5. 3. On the role of Natural Killer cell immunogenetics for the outcome of immunotherapy in acute myeloid leukemia

    Author : Brwa Ali Hussein; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Natural killer cells; Acute Myeloid Leukemia; immunotherapy; HDC IL-2; NKG2A; NK education; SNPs; NK activating receptors; HLA class I;

    Abstract : Numerous studies have revealed that natural killer cells have fundamental roles as effector cells in myeloid leukemias. Thus, understanding NK cell-related biomarkers that influence clinical outcome are warranted. READ MORE

  6. 4. Dynamic shaping of human NK cell receptor repertoires : implications for NK cell-based immunotherapy

    Author : Lisa Liu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Natural killer (NK) cells are innate lymphocytes with a potent intrinsic capacity to kill tumor cells, which makes them attractive candidates for cell-based cancer immunotherapy. Advances during the past decade have revealed that NK cells display a high degree of functional plasticity, suggesting that some subsets may be more effective in targeting cancer cells. READ MORE

  7. 5. Single cell studies of natural killer cell immune surveillance

    Author : Elin Forslund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Our immune system protects us from microbes such as viruses, bacteria and parasitic worms. The immune system also plays a key role in fighting cancer and in carrying out a function termed ‘immune surveillance’, natural killer (NK) cells patrol tissues and participate in the elimination of transformed cells and established tumors. READ MORE