Search for dissertations about: "NK cells"

Showing result 1 - 5 of 276 swedish dissertations containing the words NK cells.

  1. 1. Approaches to analyses of cytotoxic cells. And studies of their role in H. pylori infection

    Author : Josef Azem; Göteborgs universitet.; Gothenburg University.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Helicobacter pylori; mucosal immunology; stomach; duodenum; asymptomatic; duodenal ulcer; gastric adenocarcinoma; NK cells; T cells; B cells; dendritic cells; cytotoxic;

    Abstract : Helicobacter pylori infection causes chronic gastritis that may progress to peptic ulcers or gastric adenocarcinoma and thereby cause major world-wide health problems. Previous studies have shown that CD4+ T cells and the production of the cytokine IFN- × are important components of the immune response to H. pylori in humans. READ MORE

  2. 2. Dendritic cells in cancer immunotherapy

    Author : Karin Gustafsson; Göteborgs universitet.; Gothenburg University.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vaccines; dendritic cells; αDC1; PGE2DC; natural killer cells; T cells;

    Abstract : Dendritic cells (DCs) play a central role in the initiation and regulation of innate and adaptive immune responses and have increasingly been applied as vaccines for cancer patients. Ex vivo generation and antigen loading of monocyte-derived DCs allows a controlled maturation, with the aim of imprinting different DC functions that are essential for their subsequent induction of a T cell-mediated anti-tumor response. READ MORE

  3. 3. Bacterial Regulation of Peripheral Immunity Mechanistic insights from lactobacilli and Staphylococcus aureus

    University dissertation from Stockholm : Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University

    Author : Manuel Mata Forsberg; Eva Sverremark-Ekström; Monika Brunner-Weinzierl; [2019]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Immune regulation; Cytokines; T cells; gamma-delta T cells; MAIT cells; NK cells; Lactobacillus; Staphylococcus aureus; staphylococcal enterotoxins; molekylär biovetenskap; Molecular Bioscience;

    Abstract : There is a constant cross-talk between our immune system and the colonizing microbiota. The gut resident bacteria produce a broad range of molecules with regulatory activities in both local and distal tissues. Staphylococcus (S. READ MORE

  4. 4. Effects of Complement Opsonization of HIV on Dendritic Cells and Implications for the Immune Response

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Rada Ellegård; Marie Larsson; Jorma Hinkula; Johan D Söderholm; William Paxton; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; HIV; dendritic cells; complement; innate immune response; TLR signaling; T cell activation; NK cells; inflammation; antiviral response; immune evasion;

    Abstract : Dendritic cells are key players during HIV pathogenesis, and shape both the immediate immune response at the site of infection as well as directing the adaptive immune response against the virus. HIV has developed a plethora of immune evasion mechanisms that hijack dendritic cell functions, suppressing their ability to mount an accurate immune response and exploiting them for efficient viral transfer to target T cells. READ MORE

  5. 5. Shb and Its Homologues: Signaling in T Lymphocytes and Fibroblasts

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Cecilia Lindholm; Hamid Band; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Shb; T cell receptor; IL-2 receptor; PDGF receptor; cell signaling; adapter proteins; LAT; Vav; PLC-g1; SLP-76; JAK1; JAK3; Jurkat cells; T cells; NK cells; Apoptosis.; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Stimulation of the T cell receptor (TCR) induces tyrosine phosphorylation of numerous intracellular proteins, leading to activation of the interleukin-2 (IL-2) gene in T lymphocytes. Shb is a ubiquitously expressed adapter protein, with the ability to associate with the T cell receptor and several signaling proteins in T cells, including: the TCR ζ-chain, LAT, PLC-γ1, Vav, SLP-76 and Gads. READ MORE