Search for dissertations about: "NK cells"

Showing result 11 - 15 of 329 swedish dissertations containing the words NK cells.

  2. 11. T Cells and NK Cells in Coronary Artery Disease : Longitudinal and methodological studies in humans

    Author : Karin Backteman; Jan Ernerudh; Lena Jonasson; Joachim Lundahl; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Coronary artery disease (CAD) is the leading cause of death worldwide and most often due to atherosclerosis. Atherosclerosis is a chronic inflammatory process that involves the arteries, inclouding those that supply blood to the heart muscle. READ MORE

  4. 12. The leukocyte complexity and mutational landscape of periampullary adenocarcinoma. Morphology matters

    Author : Sebastian Lundgren; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; periampullary adenocarcinoma; pancreatic cancer; immune microenviroment; prognosis; macrophages; natural killer cells; natural killer T cells; T cells; B cells;

    Abstract : Background: Periampullary adenocarcinomas are a heterogenous group of tumours with poor prognosis that hasnot improved considerably the last decades. Tumour morphology, i.e. intestinal type (I-type) or pancreatobiliarytype (PB-type), has been demonstrated to be a more relevant prognostic factor than anatomical origin. READ MORE

  5. 13. Mechanisms of leukemia-induced immunosuppression

    Author : Johan Aurelius; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute myeloid leukemia; Immunosuppression; Immunotherapy; Reactive oxygen species; PARP-1; NK cells; T cells;

    Abstract : This thesis aimed to define the role of reactive oxygen species (ROS), produced by the NADPH oxidase of myeloid cells, in the regulation of lymphocyte function with focus on ROS-induced dysfunction of natural killer (NK) cells and T lymphocytes in myeloid leukemia. In Paper I, a novel mechanism is presented by which specifically activated T lymphocytes evade inactivation by ROS after antigen presentation. READ MORE

  6. 14. Live Single Cell Imaging and Analysis Using Microfluidic Devices

    Author : Mohammad Ali Khorshidi; Helene Andersson-Svahn; Håkan Jönsson; Carolina Wählby; Johan Elf; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Single cell analysis; time-lapse fluorescence imaging; automated image analysis; microwell; droplet microfluidics; NK cells; single cell tracking; migration behavior analysis; cell-cell interaction; optical microscopy; image analysis; image processing; microfluidics; immune cells; tracking; counting; morphology analysis;

    Abstract : Today many cell biological techniques study large cell populations where an average estimate of individual cells’ behavior is observed. On the other hand, single cell analysis is required for studying functional heterogeneities between cells within populations. READ MORE

  7. 15. Study of pathogenesis and immune response in human Puumala virus infection

    Author : Therese Thunberg; Clas Ahlm; Jonas Klingström; Brian Hjelle; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hantavirus; puumala virus; immune response; viral load; NK cells; T cells; cytokines; disease severity; Infectious Diseases; infektionssjukdomar;

    Abstract : Hantaviruses can cause two severe human diseases: hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). Hantaviruses are spread to humans mainly through inhalation of infectious virions, secreted from infected rodents. The human diseases are characterized by an increased capillary leakage syndrome. READ MORE