Search for dissertations about: "NMDA-receptor"
Showing result 1 - 5 of 90 swedish dissertations containing the word NMDA-receptor.
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1. Neurosteroids Induce Allosteric Effects on the NMDA Receptor : Nanomolar Concentrations of Neurosteroids Exert Non-Genomic Effects on the NMDA Receptor Complex
Abstract : The neurosteroids constitute a group of powerful hormones synthesized and acting in the central nervous system. They participate in a number of important central processes, such as memory and learning, mood and neuroprotection. READ MORE
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2. Developmental plasticity of the glutamate synapse: Roles of low frequency stimulation, hebbian induction and the NMDA receptor
Abstract : The glutamate synapse is by far the most common synapse in the brain and acts via postsynaptic AMPA, NMDA and mGlu receptors. During brain development there is a continuous production of these synapses where those partaking in activity resulting in neuronal activity are subsequently selected to establish an appropriate functional pattern of synaptic connectivity while those that do not are elimimated. READ MORE
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3. Neuronal Cell Death and Restoration in the Basal Ganglia: Implications for Huntington's and Parkinson's diseases
Abstract : Huntington's disease (HD) is a hereditary neurodegenerative disorder presenting with chorea, dementia and extensive striatal neuronal death. The mechanism through which the widely expressed mutant huntingtin mediates striatal neurotoxicity is unknown. Excitotoxicity, i.e. READ MORE
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4. Endoplasmic Reticulum Dynamic Structural Changes in Neurons: The Fission-Fusion Phenomena
Abstract : The endoplasmic reticulum (ER) is crucial for protein synthesis and protein maturation, is involved in cell stress and serves in neurons as the major intracellular Ca2+ store. Neuronal ER forms a continuous network of cisterns and tubules extending from soma to a subset of dendritic spines. READ MORE
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5. Plasticity and variation of synaptic responses in hippocampus. Role of AMPA and NMDA receptors
Abstract : It is generally believed that synaptic plasticity in the central nervous system may underlie learning and memory as well as neuronal development. The most wellstudied examples of such synaptic plasticity are long-term potentiation (LTP) andlong-term depression (LTD). READ MORE