Search for dissertations about: "NMR screening"
Showing result 1 - 5 of 29 swedish dissertations containing the words NMR screening.
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1. Studies of protein structure, dynamics and protein-ligand interactions using NMR spectroscopy
Abstract : In the first part of the thesis, protein-ligand interactions were investigated using the chaperone LcrH, from Yersinia as target protein. The structure of a peptide encompassing the amphipathic domain (residue 278-300) of the protein YopD from Yersinia was determined by NMR in 40% TFE. READ MORE
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2. The sweet side of molecular structure : NMR spectroscopic studies of glycans and their interactions with proteins
Abstract : In this thesis, within the topic of bioorganic chemistry, the molecular structure of carbohydrates has been studied. Carbohydrates, or glycans, are ubiquitous biomolecules exhibiting a wide range of biological roles. READ MORE
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3. Dynamic Sulfur Chemistry : Screening, Evaluation and Catalysis
Abstract : This thesis deals with the design, formation and evaluation of dynamic systems constructed by means of sulfur-containing reversible reactions, in organic and aqueous media and under mild conditions. In a first part, the synthesis of thioglycoside derivatives, constituting the biologically relevant starting components of the dynamic systems, is described. READ MORE
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4. Structure, dynamics and interactions of biomolecules : Investigations by NMR spectroscopy and computational methods
Abstract : In this thesis, the structure, dynamics and interactions of proteins and carbohydrates are investigated using mainly NMR spectroscopy and computer simulations. Oligosaccharides representing a Salmonella O-antigen have been synthesized and their dynamic behavior and interaction with the bacteriophage P22 tail-spike protein have been studied by NMR spectroscopy, MD and docking simulations. READ MORE
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5. Prostate Cancer Diagnosis : experimental and Clinical Studies With HRMAS NMR Spectroscopy
Abstract : A few abnormal cells found in a small piece of prostate tissue are most consequential for a man’s future. The prevalence of prostate cancer (PCa) is increasing globally. READ MORE