Search for dissertations about: "NOD-like receptors"
Showing result 1 - 5 of 12 swedish dissertations containing the words NOD-like receptors.
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1. The role and mechanism of ubiquitin system in innate immune regulation
Abstract : Pattern-recognition receptors (PRRs) include the cell surface or endosomal membrane localized Toll-like receptors (TLRs) and the cytoplasmic PRRs such as RIG-I-like receptors (RLRs), NOD-like receptors (NLRs) and cytoplasmic DNA receptors (CDRs). Triggering of PRRs culminates in the transcriptional induction of pro-inflammatory cytokines and type I interferons (IFNs) that coordinate protection against pathogens but require tight control to avert inflammatory diseases. READ MORE
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2. Chloride transport and inflammation in cystic fibrosis airways
Abstract : Cystic fibrosis (CF) is one of the most common lethal, autosomal recessive inherited diseases among Caucasians. It is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR), a chloride channel activated by cyclic AMP. READ MORE
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3. Pattern-recognition receptors in airway inflammation
Abstract : Airway inflammation is a defining feature of allergic rhinitis and asthma. Bacterial and viral infections are known to cause exacerbations of both diseases, but knowledge about the mechanisms involved is limited. READ MORE
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4. Pattern-recognition receptors and neutrophils in cancer inflammation
Abstract : Chronic inflammation, induced by the use of tobacco and alcohol, or caused by infections has long been suggested to constitute a risk factor for head and neck squamous cell carcinoma (HNSCC). The innate immunity is the first line of defense against pathogens, comprising physical and chemical barriers, anti-microbial peptides, pattern-recognition receptors (PRRs) as well as different kinds of cells, including neutrophils. READ MORE
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5. Roles in innate immune receptors : host – pathogen interactions and strengthening vaccines
Abstract : During the past decades our knowledge of innate immunology has increased drastically. This has improved our understanding about how innate immune cells can distinguish self from non-self, commensal bacteria from pathogens, and how it affects later adaptive immune responses. READ MORE