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Showing result 1 - 5 of 125 swedish dissertations matching the above criteria.

  2. 1. Neuropeptide Y - aspects of vasomotorresponses and receptor characterization

    Author : Torun Nilsson-Bergdahl; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vasoconstriction; RT-PCR; receptor characterization; potentiation; NPY Y1 receptor; NPY; mitogenesis; hypertension; human arteries; forearm blood flow; cell culture; antisense oligodeoxynucleotides; BIBP3226; vasodilatation.; Physiology; Fysiologi; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; diabetologi;

    Abstract : Abstract The aims of the present thesis were to examine neuropeptide Y (NPY) responses in different human and guinea pig vascular beds and in cultured human vascular smooth muscle cells (VSMC) and to characterize, with different NPY agonists and the specific NPY Y1 receptor antagonist (BIBP3226), the NPY receptors involved. NPY-induced strong and potent contractions in human cerebral and subcutaneous arteries and in guinea pig basilar arteries. READ MORE

  4. 2. Direct and endothelium-linked serotonergic control of vascular tone in human uterine and umbilical arteries

    Author : Caroline Karlsson; gynekologisk och prenatal ultraljudsdiagnostik Obstetrisk; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; andrology; gynaecology; Obstetrics; vascular smooth muscle; uterine artery human ; umbilical artery human ; serotonergic receptor; 5-HT; noradrenaline; endothelium; NPY; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Abstract : The serotonergic vascular control was investigated by in vitro pharmacology in the human uterine and umbilical arteries. The localisation of immunoreactive (IR) neuropeptide Y (NPY) and the influence of NPY on the adrenergic vascular effects in the human uterine artery were also studied. READ MORE

  5. 3. Winter Depression: Clinical, Psychosocial and Biochemical Characteristics

    Author : Baba Pendse; Lund Psykiatri; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NPY.; Psychiatry; clinical psychology; psychosomatics; Psykiatri; klinisk psykologi; psykosomatik; CRH; Social characteristics; Psychopathology; Temperament; Nonseasonal major depression; Suicide attempt; Winter depression; SAD;

    Abstract : Seasonal Affective Disorder with depressive episodes during the autumn/winter seasons (winter depression) is common. Outpatients with winter depression were studied regarding temperament, psychopathology, social characteristics, psychosocial functioning and the neuropeptides corticotropin - releasing hormone (CRH) and neuropeptide Y (NPY), which are known to be involved in stress-regulation. READ MORE

  6. 4. Studies of the Neuropeptide Y Receptor Y2 in Human and Zebrafish

    Author : Helena Fällmar; Dan Larhammar; Ingrid Lundell; Nina Mohell; Raquel E. Rodríguez Rodríguez; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Y2-receptor; NPY; PYY; G-protein-coupled receptor; mutagenesis; receptor binding; zebrafish; evolution; Pharmacology; Farmakologi; Farmakologi; Pharmacology;

    Abstract : The G-protein coupled receptors (GPCRs) comprise the largest family of receptors in humans and other vertebrates. They are embedded in the cell membrane and are activated by many different signaling molecules. Activation modulates cellular signal transduction pathways and influences many physiological processes. READ MORE

  7. 5. Stress Management Interventions and Predictors of Long-term Health : Prospectively Controlled Studies on Long-term Pain Patients and a Healthy Sample from IT- and Media Companies

    Author : Dan Hasson; Ulla Maria Anderberg; Töres Theorell; Ulf Lundberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Social medicine; stress; health promotion; stress management; public health; psychosocial; self-rated health; pain; intervention; web; Internet; TNF-alpha; DHEA; NPY; CgA; Socialmedicin; Social medicine; Socialmedicin;

    Abstract : This thesis reports on the effects of stress management on long-term pain patients and on a healthy sample from IT and media companies; two groups that are commonly exposed to high stress levels. Even if there are important differences between these two groups, there are similarities such as the necessity for effective stress management. READ MORE