Search for dissertations about: "NPY"
Showing result 36 - 40 of 125 swedish dissertations containing the word NPY.
-
36. Molecular evolution of the neuropeptide Y receptor family : Insights from mammals and fish
Abstract : Most genes in the genomes of vertebrates form families with multiple members that are more or less closely related. This thesis concerns investigations of the neuropeptide Y (NPY) family of peptides and the family of receptors to which these peptides bind, the NPY receptors. READ MORE
-
37. Cloning and structure-activity relationship studies of neuropeptide Y family receptors belonging to the Y1 subfamily
Abstract : Neuropeptide Y (NPY), peptide YY (PYY), and the pancreatic polypeptide (PP) belong to afamily of structurally related 36-amino-acid peptides. NPY acts as a neurotransmitter both inthe central and the peripheral nervous system and influences many functions includingfeeding, reproduction, and blood pressure while PYY and PP mainly act as hormones in thegut. READ MORE
-
38. Neuropeptides in temporomandibular joint arthritis
Abstract : Involvement of the peripheral and central nervous systems in the pathophysiology of arthritis has been suggested and neuropeptides are thought to participate in the mediation and modulation of the inflammatory process. The main objective of the clinical studies was to investigate the relationship between the presence of neuropeptides in the synovial fluid of the temporomandibular joint (TMJ) and the stomatognathic symptoms and signs, including the intra-articular temperature (IAT), in patients with TMJ arthritis. READ MORE
-
39. Leptin targets in the brain regulating body weight : receptors and down-stream mediators of leptin in neurons of the hypothalamus and brainstem
Abstract : Obesity is a disease which has become a global epidemic that is beginning to replace undernutrition and infectious diseases as the most significant contributor to ill health in the world. In particular, obesity is associated with diabetes mellitus, hypertension and coronary heart disease. READ MORE
-
40. Neuropeptide Y Y1 receptor mechanisms in sympathetic vascular control
Abstract : It was demonstrated that the Y1 receptor was the predominant vascular neuropeptide Y (NPY) receptor in pig kidney and hind limb as exogenous and endogenous NPY evoked vasoconstrictor responses that were almost or totally abolished by the selective non-peptide Y1 receptor antagonist, BIBP 3226. Furthermore, renal vasoconstriction was evoked by NPY and a peptide Y1 agonist, but not by a Y 2 agonist, and these responses were strongly reduced by another non-peptide Y, receptor antagonist, SR 120107A. READ MORE