Search for dissertations about: "NPY"

Showing result 41 - 45 of 125 swedish dissertations containing the word NPY.

  2. 41. Role of Neuropeptides and Neurotrophic Factors in Seizure Modulation

    Author : Avtandil Nanobashvili; Lund Neurologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsychology; neurophysiology; brain slice; entorhinal cortex; hippocampus; galanin; glial cell line-derived neurotrophic factor; neuropeptide Y; epilepsy; kindling; Neurology; neurofysiologi; neuropsykologi; Neurologi;

    Abstract : The presented thesis explores role of glial cell line derived neurotrophic factor family receptor a2 (GFRa2), as well as neuropeptide Y (NPY) and galanin and their receptors in modulation of seizure activity. We demonstrate that mice lacking the GFRa2 gene (GFRa2-/-) exhibit suppressed seizure generalization in traditional and rapid kindling models. READ MORE

  4. 42. Histochemical, biochemical and electrophysiological studies on dorsal root ganglion cultures : focusing on galanin, neuropeptide Y and glutamate

    Author : Nora Kerekes; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Acute and long-term DRG cultures; aFGF; BDNF; bFGF; bradykinin; excitability; galanin; glutamate; leukemia inhibitory factor; neuropeptide Y; : NGF; regeneration; whole cell patch clamp.;

    Abstract : Galanin (Gal) and neuropeptide Y (NPY) are two peptides, which are strongly up- regulated in a population of dorsal root ganglion (DRG) neurons after peripheral nerve injury (axotomy). Both peptides may be involved in the control of pain sensation, especially after nerve injury (neuropathic pain). READ MORE

  5. 43. Molecular Evolution of Neuropeptide Y Receptors in Vertebrates

    Author : Erik Salaneck; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Neuropeptide Y; Receptor; Evolution; Neurovetenskap; Neurology; Neurologi; Neurology; neurologi;

    Abstract : The three evolutionarily related peptides neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP) are ligands to at least five G-protein coupled receptors in mammals, which are denoted by numbers. NPY has many physiological effects including stimulation of appetite and regulation of circadian rhythm and blood pressure. READ MORE

  6. 44. Neuropeptide Y Receptors in Human, Guinea pig and Chicken : Cloning, in vitro Pharmacology and in situ Hybridization

    Author : Sara Holmberg; Helen Cox; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; G-protein coupled receptor; neuropeptide Y; neuropeptide Y receptor; ortholog; chicken; guinea pig; mutagenesis; receptor computer modeling; mRNA in situ hybridization; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Abstract : Neuropeptide Y (NPY) is known to influence a vast number of physiological and behavioral processes such as vasoconstriction, circadian rhythms, feeding, anxiety and memory. Peptides of the NPY family bind to five different cloned G-protein coupled receptor subtypes (Y1, 2, 4-6). READ MORE

  7. 45. The regulation of renal tubular Na+ transport is dependent on interaction between different hormones

    Author : Yoshiyuki Ohtomo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Norepinephrine; oc-adrenergic; beta-adrenergic; neuropeptide Y; Na ; K -ATPase activity; C-peptide; ontogeny;

    Abstract : Renal Na+,K+-ATPase (NKA) is of great importance for the regulation of salt metabolism and its activity can be inhibited by several natriuretic hormones. So far, the effect of antinatriuretic factors have been less well studied. READ MORE