Search for dissertations about: "NS5A"
Found 5 swedish dissertations containing the word NS5A.
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1. Study of Resistance in Hepatitis C Virus Prior to Treatment with Direct Acting Antivirals
Abstract : The rapid advancement of Hepatitis C (HCV) treatment presents a great challenge to clinicians in optimising therapy for their patients. Genotype (GT), efficacy, side-effects, drug combinations and treatment durations must be tailored to individual patients, considering comorbidities, degree of fibrosis, adherence and antiviral resistance. READ MORE
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2. Topology and membrane rearrangements of the hepatitis C virus protein NS4B
Abstract : Hepatitis C virus (HCV) is a major cause of chronic liver disease and viral hepatitis around the world. Approximately 180 million people or 3% of the world's population are infected with the virus. READ MORE
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3. Development and evaluation of new therapeutic interventions for chronic hepatitis C virus infection
Abstract : The hepatitis C virus (HCV) is a major global health problem with around 130-150 million individuals chronically infected and it is estimated that 2 millions are newly infected each year. The HCV infection is one of the major causes of liver disease and the infection is characterized by a slow and silent progression. READ MORE
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4. Generation of polyfunctional T cells against HCV by T cell redirection and vaccination
Abstract : The hepatitis C virus (HCV) is the major cause of liver disease and it is estimated that around 170 millions of people are infected worldwide. The available therapy is a combination of pegylated-interferon-alpha, ribavirin and since 2011, also NS3/4A protease inhibitors boceprevir and telaprevir. READ MORE
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5. Protein interactions involved in viral replication characterized by T7 phage display
Abstract : Protein interactions are essential for many cellular processes. By utilizing protein-protein interactions, viruses can infect their host cells and replicate. Phage display can be used for identification and characterization of protein-protein interactions. READ MORE