Search for dissertations about: "NT-3"

Showing result 1 - 5 of 40 swedish dissertations containing the word NT-3.

  2. 1. Regeneration of Peripheral Nerves. The role of protein kinases, with emphasis on neurotrophic factor stimulation

    Author : Peter Wiklund; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NT-4; NT-3; NGF; MAPK; PKG; PKA; PKC; nodose ganglion; DRG; conditioning effect; neurotrophic factors; protein kinases; peripheral; nerve regeneration; BDNF; GDNF; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Abstract : The purpose of this study was to investigate the role of protein kinases in peripheral nerve regeneration, with the use of dorsal root ganglia (DRG) and nodose ganglia explants from adult mice. The effects of neurotrophic factor stimulation and protein kinase inhibition were studied for long (days) and short term (minutes) effects. READ MORE

  4. 2. The effects of neurotrophic substances on primary sensory neurons following peripheral nerve injury

    Author : Petri Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : DRG; dorsal horn; NGF; BDNF; NT-3; substance P; calcitonin gene-related peptide; fluoride-resistant acid phosphatase; carbonic anhydrase; microglia; astroglia;

    Abstract : Sensory impulses from the periphery is transmitted by primary sensory neurons located in dorsal root and cranial nerve ganglia. The primary sensory neurons are phenotypically diverse with regard to their expression of various chemical components. READ MORE

  5. 3. On the actions of neurotrophic factors on the chromaffin cells of the adrenal medulla

    Author : Petter Förander; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Neural crest; chromaffin cells; neurotrophic factors; NGF; NT-3; NT4; CNTF; GDNF; TGFß; FGF2; glucocorticoids; Intra oculartransplantation ; primary cultures; neurite outgrowth;

    Abstract : Chromaffin cells producing adrenaline or noradrenaline are the predominant cell type in the adrenal medulla, but ganglion cells and Schwann cells are also present. All cells of the adrenal medulla are derived from the neural crest, which is a transient neuroectoderm-derived embryonic structure. READ MORE

  6. 4. Neurothrophins in the development of the gustatory system and teeth

    Author : Christopher A Nosrat; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Gustation; gustatory; taste buds; neurotrophins; NGF; BDNF; NT-3; NT-4; GDNF; GFRalpha-l; GFRalpha-2; knockout; innervation; development; tooth; tooth development; odontogene sis. Christopher A. Nosrat; 1997;

    Abstract : Flavors of taste are detected by a set of microscopical cellular aggregates called the taste buds, present in different arrangements on the upper surface of the tongue and other areas in the mouth. Taste buds are chemosensors that can detect different taste qualities such as sweet, sour, bitter, salt and umami. READ MORE

  7. 5. Gluco- and mineralocorticoid receptor regulation of regional brain neurotrophism

    Author : Anita Christiane Hansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Neurotrophins; BDNF; NT-3; bFGF; FGF receptor; immediate early genes; c-fos; antisense oligodeoxynucleotides; adrenalectomy; stress; glucocorticoids; mineralocorticoids; glucocorticoid receptor; mineralocorticoid; receptor in situ hybridization.;

    Abstract : Gluco- and mineralocorticoid hormones exert powerful actions on brain function and are important in the mediation of the stress response and the survival of hippocampal neurons. The aim of this thesis was to study the influence of glucocorticoid (GR)/mineralocorticoid receptor (MR) actions on brain neurotrophism including analyses of immediate early genes (IEGs) and of feedback responses on GR and/or MR. READ MORE