Search for dissertations about: "NTHi"

Showing result 1 - 5 of 17 swedish dissertations containing the word NTHi.

  1. 1. Haemophilus influenzae – typing, epidemiology and beta-lactam resistance

    Author : Viktor Månsson; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; benzylpenicillin; beta-lactam resistance; beta-lactams; BLNAR; capsule typing; clonal; Haemophiilus influenzae; Hib; MALDI-TOF MS; MLST; NTHi; serotyping; virulence; epidemiology;

    Abstract : Haemophilus influenzae is a common cause of respiratory tract infections such as acute otitis media (AOM), exacerbations of chronic obstructive pulmonary disease (COPD) and pneumonia. The species is subdivided into encapsulated and non-encapsulated strains, designated type a-f and nontypeable H. influenzae (NTHi), respectively. READ MORE

  2. 2. The Colonization Strategies of Nontypeable Haemophilus influenzae - Bacterial Colonization Factors and Vaccine Development

    Author : Farshid Jalalvand; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ABC-transporter; bacterial colonization; Haemophilus influenzae; Haemophilus Protein F; laminin; NTHi; pathogenesis; vaccine; virulence; vitronectin.;

    Abstract : Nontypeable Haemophilus influenzae (NTHi) is a remarkably proficient colonizer of the human respiratory tract. The aim of this thesis has been to characterize currently known, and identify novel, bacterial factors involved in the key processes of colonization and pathogenesis, namely adherence to host tissue and evasion of the host innate immunity. READ MORE

  3. 3. The structural diversity of lipopolysaccharides expressed by genetically defined clinical isolates of nontypeable Haemophilus influenzae

    Author : Martin Månsson; Elke K. H. Schweda; Jane Thomas-Oats; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Nontypeable Haemophilus influenzae NTHi ; lipopolysaccharide LPS ; nuclear magnetic resonance NMR spectroscopy; electrospray ionization mass spectrometry ESIMS ; structural analysis.;

    Abstract : Nontypeable Haemophilus influenzae (NTHi) is an important cause of otitis media and respiratory tract infections. Its lipopolysaccharide (LPS) molecule, an outer membrane component, is a major virulence factor of NTHi. The LPS molecule may also be an efficient target for antibodies which might be protective against NTHi disease. READ MORE

  4. 4. Characterization of nontypeable Haemophilus influenzae innate interactions with human cells

    Author : Irini Lazou Ahrén; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mykologi; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; inflammation; TLR4; LBP; protein D; nontypeable Haemophilus influenzae; beta-glucan;

    Abstract : Non-typeable Haemophilus influenzae (NTHi) is a human pathogen causing diseases in the upper and lower respiratory tract. Otitis media-prone children and adults with cystic fibrosis or chronic obstructive pulmonary disease, are repeatedly infected by NTHi Research in recent years brought to light the entry and survival of NTHi in epithelial cells and macrophages. READ MORE

  5. 5. Immunogenicity and protective potential of Protein D of Haemophilus influenzae against H. influenzae infection

    Author : Mustafa Akkoyunlu; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bactericidal assay; mucosal immunity; otitis media; vaccine; H. influenzae; protein D; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Both Haemophilus influenzae type b (Hib) and nontypeable H. influenzae (NTHi) are important human pathogens causing invasive and mucosal infections. Currently there are number of vaccines available against Hib infections. READ MORE