Search for dissertations about: "Nasal"

Showing result 1 - 5 of 233 swedish dissertations containing the word Nasal.

  1. 1. Nasal reactions and the school environment : Nasal patency and lavage biomarkers in relation to ventilation, cleaning and some indoor air pollutants

    Author : Robert Wålinder; Uppsala universitet; []
    Keywords : Medical sciences; acoustic rhinometry; enviromnental illness; eosinophil cationic protein ECP ; formaldehyde; lysozyme; mold; nasal lavage; nasal obstruction; N02; rhinitis; school; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; arbets- och miljömedicin; Occupational and Environmental Medicine;

    Abstract : In Sweden, 2 million persons are exposed to the school environment, and there has been reports on insufficient cleaning, and inadequate ventilation. The nasal mucosa is more easy to study than the lower airways, and rhinitis is common and possibly related to asthma. READ MORE

  2. 2. Nasal Drug Delivery : In Vitro Studies on Factors Influencing Permeability and Implications on Absorption

    Author : Cecilia Wadell; Frans Merkus; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; galenisk farmaci; Pharmaceutics;

    Abstract : Nasal delivery is a feasible alternative to oral or parenteral administration for some drugs because of the high permeability of the nasal epithelium, rapid drug absorption across this membrane and avoidance of hepatic first-pass metabolism. The main objective of this thesis was to investigate factors influencing the permeability of the nasal mucosa to various compounds and to evaluate implications for drug absorption via the nasal route. READ MORE

  3. 3. Unilateral Cleft Lip and Palate : Quality of Life and Nasal Form and Function among Adults

    Author : Maria Mani; Mats Holmström; Valdemar Skoog; Anna Andlin-Sobocki; Magnus Becker; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; unilateral cleft lip and palate; quality of life; SF-36; nasal function; nasal breathing; nasolabial appearance; cleft width; long-term results; Plastic surgery; Plastikkirurgi; Plastikkirurgi; Plastic Surgery;

    Abstract : Unilateral cleft lip and palate (UCLP) is a craniofacial malformation with functional and aesthetical impact on the face and the upper airways. The aims of the current thesis were to evaluate Quality of life (QoL) in adults treated for UCLP  (I), to objectively evaluate nasal form and function and to search for possible differences in residual nasal deformity and impairment of function between patients operated according to one-stage and two-stage palate closure (II) as well as to evaluate the relationship between professional and lay rating and patient satisfaction with nasolabial appearance (III) and to identify factors associated with lower levels of QoL and less satisfaction with nasal appearance among adults treated for UCLP (IV). READ MORE

  4. 4. Olfactory Transfer of Analgesic Drugs After Nasal Administration

    Author : Ulrika Espefält Westin; Erik Björk; Eva Brittebo; Margareta Hammarlund-Udenaes; Paolo Colombo; Uppsala universitet; []
    Keywords : Pharmaceutics; Nasal administration; Olfactory transfer; Olfactory pathways; Central nervous system; Blood-brain barrier; Nasal respiratory mucosa; Olfactory mucosa; Olfactory bulb; Horizontal Ussing chamber; Morphine; Dihydroergotamine; Rat; Mouse; Swine; Autoradiography; Viability; Powder formulations; Galenisk farmaci;

    Abstract : Nasal administration of analgesics for achieving rapid pain relief is currently a topic of great interest. The blood-brain barrier (BBB) restricts access to the central nervous system (CNS) for several central-acting drugs, such as morphine and dihydroergotamine, which results in a substantial effect delay. READ MORE

  5. 5. Evaluation of nasal speech : a study of assessments by speech-language pathologists, untrained listeners and nasometry

    Author : Karin Brunnegård; Jan van Doorn; Anette Lohmander; Fiona Gibbon; Umeå universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hypernasality; auditory perceptual evaluation; reliability; nasometer; nasalance; Logopedics and phoniatrics; Logopedi och foniatrik;

    Abstract : Excessive nasal resonance in speech (hypernasality) is a disorder which may have negative communicative and social consequences for the speaker. Excessive nasal resonance is often associated with cleft lip and palate, velopharyngeal impairment, dysarthria or hearing impairment. READ MORE