Search for dissertations about: "Natural target therapy"

Showing result 1 - 5 of 97 swedish dissertations containing the words Natural target therapy.

  1. 1. Spectroscopic techniques for photodynamic therapy dosimetry

    Author : Ann Johansson; Atomfysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Atomic and molecular physics; diffuse light spectroscopy; photodynamic therapy; biomedical optics; Atom- och molekylärfysik;

    Abstract : Photodynamic therapy (PDT) as a cancer treatment modality relies on the simultaneous presence of three components; light, photosensitiser and oxygen. Once excited by the light, the photosensitiser can interact with oxygen, leading to the formation of toxic oxygen species. READ MORE

  2. 2. Modeling normal and malignant hematopoiesis in vitro. To screen for extrinsic regulators and differentiation therapy

    Author : Simon Hultmark; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; acute myeloid leukaemia; Hematologi; stem cells; differentiation induction; leukaemia; treatment; small molecule drugs; PKC; FLT3; shRNA; small molecule inhibitor; Small Molecule Libraries; MEK ERK pathway; natural product; co-culture; drug screening; combination therapy;

    Abstract : The incredible thing with blood stem cells, also known as hematopoietic stem cells (HSC), is that they can restore normal hematopoiesis in patients that need a new blood system. Since a prerequisite for successful transplantation is immune compatibility, it requires large donor registries to find a suitable match for a recipient. READ MORE

  3. 3. On Quality in Radiotherapy Treatment Plan Optimisation

    Author : Hunor Benedek; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Pareto optimisation; Pareto fronts; Dose prediction; Machine learning; Deliverable treatment plans; Volumetric modulated arc therapy; IMRT; patient-specific plan quality; plan quality; Multi Criteria Optimisation; Automated Treatment Planning;

    Abstract : Radiotherapy is one of the essential treatments used in the fight against cancer. The goal of radiotherapy is to deliver a high dose of ionising radiation to the tumour volume and at the same time minimise the effect on healthy tissue by reducing the radiation to critical organs. READ MORE

  4. 4. Radiation therapy of upper gastrointestinal cancers with scanned proton beams : A treatment planning study

    Author : Gracinda Mondlane; Albert Siegbahn; Michael Gubanski; Iuliana Toma-Dasu; Crister Ceberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Treatment planning; gastric cancer; liver metastases; photon beam therapy; proton beam therapy; dosimetric comparison; normal tissue complication probability; risk of radiation-induced secondary cancer; patient selection; Medical Radiation Physics; medicinsk strålningsfysik;

    Abstract : Proton beam therapy (PBT), using scanned beams, is an emerging modality used for the treatment of cancer. The clinical advantages of PBT, compared to commonly used photon beam therapy, have been demonstrated in different studies. READ MORE

  5. 5. Robust optimization of radiation therapy accounting for geometric uncertainty

    Author : Albin Fredriksson; Anders Forsgren; Timothy C. Y. Chan; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Optimization; intensity-modulated proton therapy; uncertainty; robust planning; setup error; range error; intensity-modulated radiation therapy; multicriteria optimization;

    Abstract : Geometric errors may compromise the quality of radiation therapy treatments. Optimization methods that account for errors can reduce their effects.The first paper of this thesis introduces minimax optimization to account for systematic range and setup errors in intensity-modulated proton therapy. READ MORE