Search for dissertations about: "Negative symptoms schizophrenia"

Showing result 1 - 5 of 31 swedish dissertations containing the words Negative symptoms schizophrenia.

  2. 1. Dopaminergic stabilizers for the treatment of schizophrenia. Rat studies focusing on negative symptoms and mechanisms of action

    Author : Johan P. Rung; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ACR16; dopaminergic stabilizers; -MK-801; motor activity; negative symptoms; - -OSU6162; prolactin; rat; schizophrenia; social withdrawal;

    Abstract : Schizophrenia is a severe mental disorder manifested by positive, negative and cognitive symptoms. Current antipsychotic drugs have poor effects on negative and cognitive symptoms, thus necessitating the development of new antipsychotic treatments. Dopaminergic stabilizers constitute a novel concept for the treatment of schizophrenia. READ MORE

  4. 2. Finding improved drug strategies for schizophrenia : Preclinical studies on lumateperone and sodium nitroprusside

    Author : Joep Titulaer; Åsa Konradsson-Geuken; Anne-Lie Svensson; Erika Roman; Kent Jardemark; Joshua Beckmann; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; schizophrenia; lumateperone; sodium nitroprusside; antipsychotic drugs; Farmaceutisk vetenskap; Pharmaceutical Science; Pharmacology; Farmakologi; Psychiatry; Psykiatri;

    Abstract : Schizophrenia is a severe psychiatric disorder affecting approximately 20 million people worldwide. The disease consists of positive symptoms e.g. hallucinations, negative symptoms such as anhedonia, and cognitive deficits, e. READ MORE

  5. 3. Occupational Perspectives on Health in People with Schizophrenia

    Author : Ulrika Bejerholm; Hållbar vardag och hälsa i ett livsperspektiv; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; revalidation; kinesitherapy; Physical medicine; Medicin människa och djur ; Medicine human and vertebrates ; Mental Health; Time Use; Schizophrenia; rehabilitation; Rehabilitering medicinsk och social ;

    Abstract : The thesis has provided with systematic information about how people with schizophrenia live their everyday life, and the results have shown significant relationships between occupational perspectives and health. The thesis departed in two in-depth studies that concerned time use and occupational engagement in relation to what people with schizophrenia do in their everyday life, with whom they are with, where they are and how they perceive and experience what they do, as reflected by time-use diaries. READ MORE

  6. 4. Dopaminergic lnterference for Treatment of Schizophrenia and Alcohol Use Disorder - an experimental study in rats

    Author : Klara Danielsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dopamine; striatum; addiction; schizophrenia;

    Abstract : The neurotransmitter dopamine is involved in several different physiological functions as well as pathological conditions. Two conditions that have been suggested to be related to a low dopaminergic tone in the ventral striatum are substance use disorder, and negative symptoms in schizophrenia, both of which are difficult to treat. READ MORE

  7. 5. Negative symptoms, repetitive transcranial magnetic stimulation and heart rate variability in schizophrenia and depression

    Author : Johan Bengtsson; Robert Bodén; Jonas Persson; Erik Olsson; Caroline Wass; Jimmi Nielsen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; negative symptoms; psychotic disorders; affective disorders; non-invasive brain stimulation; transdiagnostics; psychometrics; autonomic nervous system; Psychiatry; Psykiatri;

    Abstract : Negative symptoms comprise anhedonia, avolition, and blunted affect. Although first described in schizophrenia, these symptoms share phenomenology with the depressive state. Pharmacological treatment has not been successful in reducing negative symptoms. READ MORE