Search for dissertations about: "Neostriatum"

Found 3 swedish dissertations containing the word Neostriatum.

  2. 1. Characterization of neuropeptide, monoamine, and amino acid release in the basal ganglia of the rat : neuronal dependence and reciprocal interactions

    Author : Zhi-Bing You; Karolinska Institutet; Karolinska Institutet; []
    Keywords : amino acids cholecystokinin dopamine dynorphin microdialysis morphineneostriatum rat substantia nigra.;

    Abstract : Functional interactions in the basal ganglia of rats were characterized with in vivomicrodialysis. The study was mainly focused on the dynorphin and cholecystokinin (CCK) systems. The extracellular levels of both dynorphin B and CCK were found in the pM range inthe neostriatum and substantia nigra under basal conditions. READ MORE

  4. 2. Experimental studies on the sources, pathways and targets for volume transmission in the rat brain

    Author : Anders Jansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : volume transmission; extracellular space; monoamines; Dl D2 receptors; 5HT2A receptors; nitric oxide; interleukin-1ß; cholecystokinin; galanin;

    Abstract : Volume transmission has been defined as the three-dimensional diffusion or convection of transmitters in the extracellular space (ECS) and cerebrospinal fluid (CSF) over a larger distance than the synaptic cleft. The regional localization of dopamine (DA) nerve terminals and dopamine Dl and D2 receptors in nucleus accumbens were studied in detail using double immuno-labelling. READ MORE

  5. 3. In vivo quantification of extrastriatal dopamine D2 receptors in the human brain

    Author : Hans Olsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : FLB 457; positron emission tomography; pituitary; receptor density; affinity; benzamide; Scatchard; saturation; receptor occupancy;

    Abstract : The dopamine D2 receptor subtype attracts considerable attention in research on the patophysiology and drug treatment of several neuropsychiatric disorders, such as schizophrenia and Parkinson's disease. The brain imaging technology Positron Emission Tomography (PET) has since long allowed for reliable quantification of the high density of dopamine D2 receptors in large brain structures such as the neostriatum. READ MORE